2LAJ
Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide
Summary for 2LAJ
| Entry DOI | 10.2210/pdb2laj/pdb |
| NMR Information | BMRB: 17529 |
| Descriptor | E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3 (2 entities in total) |
| Functional Keywords | cdk, signal transduction, ligase-transcription regulator complex, ligase/transcription regulator |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cytoplasm: Q96PU5 P84022 |
| Total number of polymer chains | 2 |
| Total formula weight | 6323.84 |
| Authors | Macias, M.J.,Aragon, E.,Goerner, N.,Zaromytidou, A.,Xi, Q.,Escobedo, A.,Massague, J. (deposition date: 2011-03-16, release date: 2011-07-06, Last modification date: 2023-06-14) |
| Primary citation | Aragon, E.,Goerner, N.,Zaromytidou, A.I.,Xi, Q.,Escobedo, A.,Massague, J.,Macias, M.J. A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25:1275-1288, 2011 Cited by PubMed: 21685363DOI: 10.1101/gad.2060811 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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