2LAJ
Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | E3 ubiquitin-protein ligase NEDD4-like | polymer | 44 | 5210.9 | 1 | UniProt (Q96PU5) Pfam (PF00397) In PDB | Homo sapiens (human) | NEDD4.2, Nedd4-2 |
| 2 | B | Mothers against decapentaplegic homolog 3 | polymer | 10 | 1113.0 | 1 | UniProt (P84022) In PDB | Homo sapiens | MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, Smad3, hSMAD3 |
Sequence modifications
A: 476 - 515 (UniProt: Q96PU5)
| PDB | External Database | Details |
|---|---|---|
| Gly 472 | - | expression tag |
| Ala 473 | - | expression tag |
| Met 474 | - | expression tag |
| Glu 475 | - | expression tag |
| Tyr 496 | Ile 516 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 6323.8 | |
| All* | Total formula weight | 6323.8 |
