2LF0
 
 | | Solution structure of sf3636, a two-domain unknown function protein from Shigella flexneri 2a, determined by joint refinement of NMR, residual dipolar couplings and small-angle X-ray scattering, NESG target SfR339/OCSP target sf3636 | | Descriptor: | Uncharacterized protein yibL | | Authors: | Wu, B, Lemak, A, Yee, A, Lee, H, Gutmanas, A, Semesi, A, Garcia, M, Fang, X, Wang, Y, Prestegard, J.H, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) | | Deposit date: | 2011-06-27 | | Release date: | 2011-07-13 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR, SOLUTION SCATTERING | | Cite: | Solution structure of sf3636, a two-domain unknown function protein from Shigella flexneri 2a, determined by joint refinement of NMR, residual dipolar couplings and small-angle X-ray scattering
To be Published
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4GL2
 | | Structural Basis for dsRNA duplex backbone recognition by MDA5 | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(*AP*UP*CP*CP*GP*CP*GP*GP*CP*CP*CP*U)-3'), ... | | Authors: | Wu, B, Hur, S. | | Deposit date: | 2012-08-13 | | Release date: | 2013-01-09 | | Last modified: | 2013-02-06 | | Method: | X-RAY DIFFRACTION (3.557 Å) | | Cite: | Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5.
Cell(Cambridge,Mass.), 152, 2013
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7W0I
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4P4H
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7X5C
 | | Solution structure of Tetrahymena p75OB1-p50PBM | | Descriptor: | Telomerase associated protein p50PBM, Telomerase-associated protein p75OB1 | | Authors: | Wu, B, Tang, T, Xue, H.J, Wu, J, Lei, M. | | Deposit date: | 2022-03-04 | | Release date: | 2022-10-19 | | Method: | SOLUTION NMR | | Cite: | Association of the CST complex and p50 in Tetrahymena is crucial for telomere maintenance
Structure, 2022
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3KUY
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5YRN
 | | Structure of RIP2 CARD domain | | Descriptor: | Receptor-interacting serine/threonine-protein kinase 2 | | Authors: | Wu, B, Gong, Q. | | Deposit date: | 2017-11-09 | | Release date: | 2018-11-14 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis of RIP2 activation and signaling.
Nat Commun, 9, 2018
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2LF6
 | | Solution NMR structure of HopABPph1448_220_320 from Pseudomonas syringae pv. phaseolicola str. 1448A, Midwest Center for Structural Genomics target APC40132.4 and Northeast Structural Genomics Consortium target PsT3A | | Descriptor: | Effector protein hopAB1 | | Authors: | Wu, B, Yee, A, Houliston, S, Semesi, A, Garcia, M, Singer, A.U, Savchenko, A, Montelione, G.T, Joachimiak, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG), Ontario Centre for Structural Proteomics (OCSP) | | Deposit date: | 2011-06-28 | | Release date: | 2011-07-13 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural Analysis of HopPmaL Reveals the Presence of a Second Adaptor Domain Common to the HopAB Family of Pseudomonas syringae Type III Effectors.
Biochemistry, 51, 2012
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2K2C
 | | Solution NMR structure of N-terminal domain of human pirh2. Northeast Structural Genomics Consortium (NESG) target HT2A | | Descriptor: | RING finger and CHY zinc finger domain-containing protein 1, ZINC ION | | Authors: | Wu, B, Lemak, A, Sheng, Y, Karra, M, Srisailam, S, Sunnerhagen, M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-03-31 | | Release date: | 2008-04-15 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Molecular basis of Pirh2-mediated p53 ubiquitylation.
Nat.Struct.Mol.Biol., 15, 2008
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2KDB
 | | Solution Structure of human ubiquitin-like domain of Herpud2_9_85, Northeast Structural Genomics Consortium (NESG) target HT53A | | Descriptor: | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein | | Authors: | Wu, B, Yee, A, Fares, C, Lemak, A, Gutmanas, A, Doherty, R, Semesi, A, Dhe-Paganon, S, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC) | | Deposit date: | 2009-01-06 | | Release date: | 2009-02-10 | | Last modified: | 2012-05-23 | | Method: | SOLUTION NMR | | Cite: | Structure of human homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 2 (Herpud2 or Herp)
To be Published
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2L76
 | | Solution NMR structure of human NFATC2IP ubiquitin-like domain, NFATC2IP_244_338, NESG target HT65A/OCSP target hs00387_244_338/SGC-toronto | | Descriptor: | NFATC2-interacting protein | | Authors: | Wu, B, Yee, A, Houliston, S, Doherty, R, Semesi, A, Dhe-Paganon, S, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) | | Deposit date: | 2010-12-03 | | Release date: | 2010-12-22 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Human NFATC2IP ubiquitin-like domains
To be Published
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2LF3
 | | Solution NMR structure of HopPmaL_281_385 from Pseudomonas syringae pv. maculicola str. ES4326, Midwest Center for Structural Genomics target APC40104.5 and Northeast Structural Genomics Consortium target PsT2A | | Descriptor: | Effector protein hopAB3 | | Authors: | Wu, B, Yee, A, Houliston, S, Semesi, A, Garcia, M, Singer, A.U, Savchenko, A, Montelione, G.T, Joachimiak, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG), Ontario Centre for Structural Proteomics (OCSP) | | Deposit date: | 2011-06-28 | | Release date: | 2011-07-13 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural Analysis of HopPmaL Reveals the Presence of a Second Adaptor Domain Common to the HopAB Family of Pseudomonas syringae Type III Effectors.
Biochemistry, 51, 2012
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5ZUU
 | | Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA | | Descriptor: | 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | | Authors: | Wu, B, Nie, H, Li, S, Patel, D.J. | | Deposit date: | 2018-05-08 | | Release date: | 2019-05-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis.
Mol Plant, 2021
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6LQZ
 | | Solution structure of Taf14ET-Sth1EBMC | | Descriptor: | Nuclear protein STH1/NPS1, Transcription initiation factor TFIID subunit 14 | | Authors: | Wu, B, Chen, G, Chen, Y. | | Deposit date: | 2020-01-15 | | Release date: | 2020-08-05 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Taf14 recognizes a common motif in transcriptional machineries and facilitates their clustering by phase separation.
Nat Commun, 11, 2020
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7Q3N
 | | Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ... | | Authors: | Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B. | | Deposit date: | 2021-10-28 | | Release date: | 2022-03-16 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
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7PFP
 | | Full-length cryo-EM structure of the native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B. | | Deposit date: | 2021-08-11 | | Release date: | 2022-03-16 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
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6TQL
 | | Cryo-EM of elastase-treated human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L. | | Deposit date: | 2019-12-16 | | Release date: | 2020-11-04 | | Last modified: | 2021-03-03 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Cryo-EM structure of native human uromodulin, a zona pellucida module polymer.
Embo J., 39, 2020
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6TQK
 | | Cryo-EM of native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, ... | | Authors: | Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L. | | Deposit date: | 2019-12-16 | | Release date: | 2020-11-04 | | Last modified: | 2021-03-03 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Cryo-EM structure of native human uromodulin, a zona pellucida module polymer.
Embo J., 39, 2020
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8X5J
 | | The Crystal Structure of PARP5A from Biortus. | | Descriptor: | 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, Poly [ADP-ribose] polymerase, ... | | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | | Deposit date: | 2023-11-17 | | Release date: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure of PARP5A from Biortus.
To Be Published
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8X72
 | | The Crystal Structure of PLK1 from Biortus. | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Wang, F, Cheng, W, Yuan, Z, Lin, D, Wu, B. | | Deposit date: | 2023-11-22 | | Release date: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Crystal Structure of PLK1 from Biortus.
To Be Published
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8XN6
 | | The Crystal Structure of GSK3b from Biortus. | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glycogen synthase kinase-3 beta, ... | | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | | Deposit date: | 2023-12-29 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Crystal Structure of GSK3b from Biortus.
To Be Published
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8XU5
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8YHK
 | | The Crystal Structure of P21-Activated Kinases Pak4 from Biortus | | Descriptor: | Serine/threonine-protein kinase PAK 4, TRIETHYLENE GLYCOL | | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Wu, B. | | Deposit date: | 2024-02-28 | | Release date: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The Crystal Structure of P21-Activated Kinases Pak4 from Biortus
To Be Published
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8YHH
 | | The Crystal Structure of Mitotic Kinesin Eg5 from Biortus | | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Wu, B. | | Deposit date: | 2024-02-28 | | Release date: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The Crystal Structure of Mitotic Kinesin Eg5 from Biortus
To Be Published
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1N1A
 | | Crystal Structure of the N-terminal domain of human FKBP52 | | Descriptor: | FKBP52 | | Authors: | Li, P, Ding, Y, Wu, B, Shu, C, Shen, B, Rao, Z. | | Deposit date: | 2002-10-16 | | Release date: | 2002-12-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the N-terminal domain of human FKBP52.
Acta Crystallogr.,Sect.D, 59, 2003
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