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2QLP
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BU of 2qlp by Molmil
Bifunctional dCTP deaminase:dUTPase from Mycobacterium tuberculosis, apo form
分子名称: Deoxycytidine triphosphate deaminase, PENTAETHYLENE GLYCOL
著者Christophersen, S, Harris, P, Willemoes, M.
登録日2007-07-13
公開日2008-02-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis
J.Mol.Biol., 376, 2007
4XJC
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BU of 4xjc by Molmil
dCTP deaminase-dUTPase from Bacillus halodurans
分子名称: DI(HYDROXYETHYL)ETHER, Deoxycytidine triphosphate deaminase, MAGNESIUM ION, ...
著者Oehlenschlaeger, C, Loevgreen, M, Willemoes, M, Harris, P.
登録日2015-01-08
公開日2015-03-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Bacillus halodurans Strain C125 Encodes and Synthesizes Enzymes from Both Known Pathways To Form dUMP Directly from Cytosine Deoxyribonucleotides.
Appl.Environ.Microbiol., 81, 2015
3NVA
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BU of 3nva by Molmil
Dimeric form of CTP synthase from Sulfolobus solfataricus
分子名称: CTP synthase
著者Harris, P, Willemoes, M, Lauritsen, I, Johansson, E, Jensen, K.F.
登録日2010-07-08
公開日2010-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus
Acta Crystallogr.,Sect.F, 67, 2011
4A6A
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BU of 4a6a by Molmil
A115V variant of dCTP deaminase-dUTPase from Mycobacterium tuberculosis in complex with dTTP
分子名称: DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
著者Lovgreen, M.N, Ucar, E, Willemoes, M, Harris, P.
登録日2011-11-01
公開日2012-10-10
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Dttp Inhibition of the Bifunctional Dctp Deaminase- Dutpase from Mycobacterium Tuberculosis is Ph Dependent: Kinetic Analyses and Crystal Structure of A115V Variant
To be Published
8QZK
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BU of 8qzk by Molmil
Catalytic core of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) concieved by deep network hallucination: dEngBF4 Hexagonal form
分子名称: ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE
著者Aghajari, N, Hansen, A.L, Thiesen, F.F, Crehuet, R, Marcos, E, Willemoes, M.
登録日2023-10-27
公開日2024-03-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination.
Acs Synth Biol, 13, 2024
2QXX
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BU of 2qxx by Molmil
Bifunctional dCTP deaminase: dUTPase from Mycobacterium tuberculosis in complex with dTTP
分子名称: Deoxycytidine triphosphate deaminase, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ...
著者Christophersen, S, Harris, P, Willemoes, M.
登録日2007-08-13
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis.
J.Mol.Biol., 376, 2008
2V9X
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E138D variant of Escherichia coli dCTP deaminase in complex with dUTP
分子名称: DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Thymark, M, Johansson, E, Larsen, S, Willemoes, M.
登録日2007-08-28
公開日2007-11-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mutational Analysis of the Nucleotide Binding Site of Escherichia Coli Dctp Deaminase.
Arch.Biochem.Biophys., 470, 2008
1XS4
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dCTP deaminase from Escherichia coli- E138A mutant enzyme in complex with dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION
著者Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M.
登録日2004-10-18
公開日2004-12-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
J.Biol.Chem., 280, 2005
3GF0
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BU of 3gf0 by Molmil
Bifunctional dCTP deaminase-dUTPase mutant enzyme variant E145Q from Methanocaldococcus jannaschii in complex with pyrophosphate and magnesium
分子名称: MAGNESIUM ION, PYROPHOSPHATE 2-, dCTP deaminase, ...
著者Siggaard, J.H.B, Johansson, E, Vognsen, T, Helt, S.S, Harris, P, Willemoes, M.
登録日2009-02-26
公開日2009-03-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Pre-steady State Kinetic and Structural Evidence for a Concerted Biofunctionality in dCTP deaminase-dUTPase from Methanocaldococcus jannaschii
To be Published
1XS6
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BU of 1xs6 by Molmil
dCTP deaminase from Escherichia coli. E138A mutant enzyme in complex with dUTP
分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION
著者Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M.
登録日2004-10-18
公開日2004-12-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
J.Biol.Chem., 280, 2005
1XS1
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BU of 1xs1 by Molmil
dCTP deaminase from Escherichia coli in complex with dUTP
分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION
著者Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M.
登録日2004-10-18
公開日2004-12-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
J.Biol.Chem., 280, 2005
2G3M
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BU of 2g3m by Molmil
Crystal structure of the Sulfolobus solfataricus alpha-glucosidase MalA
分子名称: Alpha-glucosidase
著者Ernst, H.A, Lo Leggio, L, Willemoes, M, Leonard, G, Blum, P, Larsen, S.
登録日2006-02-20
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of the Sulfolobus solfataricus alpha-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31.
J.Mol.Biol., 358, 2006
2G3N
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BU of 2g3n by Molmil
Crystal structure of the Sulfolobus solfataricus alpha-glucosidase MalA in complex with beta-octyl-glucopyranoside
分子名称: Alpha-glucosidase, octyl beta-D-glucopyranoside
著者Ernst, H.A, Lo Leggio, L, Willemoes, M, Leonard, G, Blum, P, Larsen, S.
登録日2006-02-20
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of the Sulfolobus solfataricus alpha-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31.
J.Mol.Biol., 358, 2006
1UX1
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BU of 1ux1 by Molmil
Bacillus subtilis cytidine deaminase with a Cys53His and an Arg56Gln substitution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ...
著者Johansson, E, Neuhard, J, Willemoes, M, Larsen, S.
登録日2004-02-18
公開日2004-05-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase
Biochemistry, 43, 2004
1UWZ
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BU of 1uwz by Molmil
Bacillus subtilis cytidine deaminase with an Arg56 - Ala substitution
分子名称: CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ZINC ION
著者Johansson, E, Neuhard, J, Willemoes, M, Larsen, S.
登録日2004-02-18
公開日2004-05-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase
Biochemistry, 43, 2004
1UX0
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BU of 1ux0 by Molmil
Bacillus subtilis cytidine deaminase with an Arg56 - Gln substitution
分子名称: CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ZINC ION
著者Johansson, E, Neuhard, J, Willemoes, M, Larsen, S.
登録日2004-02-18
公開日2004-05-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase
Biochemistry, 43, 2004
2J4Q
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BU of 2j4q by Molmil
Crystal structure of a E138A Escherichia coli dCTP deaminase mutant enzyme in complex with dTTP
分子名称: DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ...
著者Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M.
登録日2006-09-05
公開日2007-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme
FEBS J., 274, 2007
2J4H
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BU of 2j4h by Molmil
Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme
分子名称: DEOXYCYTIDINE DIPHOSPHATE, DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION
著者Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M.
登録日2006-08-31
公開日2007-08-07
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme
FEBS J., 274, 2007
1VST
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BU of 1vst by Molmil
Symmetric Sulfolobus solfataricus uracil phosphoribosyltransferase with bound PRPP and GTP
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kadziola, A.
登録日2009-02-09
公開日2009-09-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus
J.Mol.Biol., 393, 2009
2QPS
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BU of 2qps by Molmil
"Sugar tongs" mutant Y380A in complex with acarbose
分子名称: Alpha-amylase type A isozyme, CALCIUM ION
著者Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
登録日2007-07-25
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007
5J7D
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BU of 5j7d by Molmil
Computationally Designed Thioredoxin dF106
分子名称: COPPER (II) ION, Designed Thioredoxin dF106
著者Horowitz, S, Johansen, N, Olsen, J.G, Winther, J.R.
登録日2016-04-06
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template.
J.Mol.Biol., 428, 2016
3G6W
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BU of 3g6w by Molmil
Asymetric GTP bound structure of UPRTase from Sulfolobus solfataricus containing PRPP-mg2+ in half of the active sites and R5P and PPi in the other half
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 5-O-phosphono-alpha-D-ribofuranose, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Kadziola, A, Christoffersen, S.
登録日2009-02-09
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus
J.Mol.Biol., 393, 2009
8QYE
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BU of 8qye by Molmil
Catalytic core of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) concieved by deep network hallucination: dEngBF4
分子名称: 1,2-ETHANEDIOL, ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE
著者Aghajari, N.
登録日2023-10-25
公開日2024-03-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination.
Acs Synth Biol, 13, 2024
2QPU
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Sugar tongs mutant S378P in complex with acarbose
分子名称: 1,2-ETHANEDIOL, 1,5-anhydro-4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-methylcyclohexyl]amino}-alpha-D-glucopyranosyl)-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
著者Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
登録日2007-07-25
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007
2HXB
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dCTP deaminase-dUTPase from Methanocaldococcus jannaschii
分子名称: dCTP deaminase, dUMP-forming
著者Bynck, J.H, Johansson, E.
登録日2006-08-03
公開日2007-08-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural evidence for a concerted Bifunctionality in dCTP deaminase-dUTPase from Methanocaldococcus jannaschii
To be Published

 

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