3G6W

Asymetric GTP bound structure of UPRTase from Sulfolobus solfataricus containing PRPP-mg2+ in half of the active sites and R5P and PPi in the other half

Summary for 3G6W

Entry DOI	10.2210/pdb3g6w/pdb
Related	1VST 1XTT 1XTU 1XTV
Descriptor	Uracil phosphoribosyltransferase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	allosteric regulation, tetramer, sulfolobus solfataricus, phosphoribosyltransferase, prpp, r5p, gtp, pop, magnesium, glycosyltransferase, transferase
Biological source	Sulfolobus solfataricus
Total number of polymer chains	4
Total formula weight	100729.72
Authors	Kadziola, A.,Christoffersen, S. (deposition date: 2009-02-09, release date: 2009-09-01, Last modification date: 2023-11-01)
Primary citation	Christoffersen, S.,Kadziola, A.,Johansson, E.,Rasmussen, M.,Willemoes, M.,Jensen, K.F. Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus J.Mol.Biol., 393:464-477, 2009 Cited by PubMed: 19683539 DOI: 10.1016/j.jmb.2009.08.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation