3GF0

Bifunctional dCTP deaminase-dUTPase mutant enzyme variant E145Q from Methanocaldococcus jannaschii in complex with pyrophosphate and magnesium

Replaces:  2HXE

Summary for 3GF0

• Entry DOI: 10.2210/pdb3gf0/pdb
• Related: 1OGH 2HXB 2HXD
• Descriptor: dCTP deaminase, dUMP-forming, MAGNESIUM ION, PYROPHOSPHATE 2-, ... (4 entities in total)
• Functional Keywords: dctp deaminase-dutpase, bifunctional hydrolase, magnesium, nucleotide metabolism, hydrolase
• Biological source: Methanocaldococcus jannaschii
• Total number of polymer chains: 1
• Total formula weight: 23734.05

Authors

Siggaard, J.H.B.,Johansson, E.,Vognsen, T.,Helt, S.S.,Harris, P.,Willemoes, M. (deposition date: 2009-02-26, release date: 2009-03-10, Last modification date: 2023-11-01)

• Primary citation: Siggaard, J.H.B.,Johansson, E.,Vognsen, T.,Helt, S.S.,Harris, P.,Larsen, S.,Willemoes, M.; Pre-steady State Kinetic and Structural Evidence for a Concerted Biofunctionality in dCTP deaminase-dUTPase from Methanocaldococcus jannaschii; To be Published,

Experimental method

X-RAY DIFFRACTION (2.62 Å)