2QXX
Bifunctional dCTP deaminase: dUTPase from Mycobacterium tuberculosis in complex with dTTP
Summary for 2QXX
| Entry DOI | 10.2210/pdb2qxx/pdb |
| Related | 2QLP |
| Descriptor | Deoxycytidine triphosphate deaminase, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
| Functional Keywords | distorted beta barrel, hydrolase, nucleotide metabolism |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 2 |
| Total formula weight | 43510.99 |
| Authors | Christophersen, S.,Harris, P.,Willemoes, M. (deposition date: 2007-08-13, release date: 2008-02-19, Last modification date: 2023-08-30) |
| Primary citation | Helt, S.S.,Thymark, M.,Harris, P.,Aagaard, C.,Dietrich, J.,Larsen, S.,Willemoes, M. Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis. J.Mol.Biol., 376:554-569, 2008 Cited by PubMed: 18164314DOI: 10.1016/j.jmb.2007.11.099 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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