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8G90
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BU of 8g90 by Molmil
LaM domain of human LARP1 in complex with Sp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
7SOR
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BU of 7sor by Molmil
LaM domain of human LARP1 in complex with AAA RNA
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Isoform 2 of La-related protein 1, ...
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOT
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BU of 7sot by Molmil
LaM domain of human LARP1 in complex with AAAAAA oligonucleotide
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOP
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BU of 7sop by Molmil
LaM domain of human LARP1 in complex with AAAUAA RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*UP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOV
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BU of 7sov by Molmil
LaM domain of human LARP1 in complex with AAAAAAAAAAA RNA polynucleotide
Descriptor: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOO
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BU of 7soo by Molmil
LaM domain of human LARP1
Descriptor: Isoform 2 of La-related protein 1, SODIUM ION, SULFATE ION
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOU
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BU of 7sou by Molmil
LaM domain of human LARP1 in complex with AAAAAA polynucleotide
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOS
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BU of 7sos by Molmil
LaM domain of human LARP1 in complex with AAAA RNA
Descriptor: Isoform 2 of La-related protein 1, POTASSIUM ION, RNA (5'-R(*AP*AP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOQ
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BU of 7soq by Molmil
LaM domain of human LARP1 in complex with AAA RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
2H9S
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BU of 2h9s by Molmil
Crystal Structure of Homo-DNA and Nature's Choice of Pentose over Hexose in the Genetic System
Descriptor: 5'-D(*(XCT)P*(XGU)P*(XAD)P*(XAD)P*(XTH)P*(XTH)P*(XCT)P*(XGU))-3', MAGNESIUM ION
Authors:Egli, M, Pallan, P.S.
Deposit date:2006-06-11
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system.
J.Am.Chem.Soc., 128, 2006
5VXQ
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BU of 5vxq by Molmil
X-Ray crystallography structure of the parallel stranded duplex formed by 5-rA5-dA-rA5
Descriptor: AMMONIUM ION, DNA/RNA (5'-R(*AP*AP*AP*AP*A)-D(P*A)-R(P*AP*AP*AP*AP*A)-3')
Authors:Xie, J, Chen, Y, Wei, X, Kozlov, G, Gehring, K.
Deposit date:2017-05-23
Release date:2017-08-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.002 Å)
Cite:Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.
Nucleic Acids Res., 45, 2017
1HO6
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BU of 1ho6 by Molmil
CHIMERIC ARABINONUCLEIC ACID (ANA) HAIRPIN WITH ANA/RNA HYBRID STEM
Descriptor: DNA/RNA (5'-R(*GP*GP*AP*C)-D(P*TP*TP*CP*G)-(P*(GAO)P*(UAR)P*(CAR)P*(CAR)-3')
Authors:Denisov, A.Y, Gehring, K.
Deposit date:2000-12-08
Release date:2001-11-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.
Nucleic Acids Res., 29, 2001
1HOQ
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BU of 1hoq by Molmil
CHIMERIC RNA/DNA HAIRPIN
Descriptor: DNA/RNA (5'-R(*GP*GP*AP*C)-D(P*TP*TP*CP*GP*GP*TP*CP*C)-3')
Authors:Denisov, A.Y, Gehring, K.
Deposit date:2000-12-11
Release date:2001-11-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.
Nucleic Acids Res., 29, 2001
2LSC
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BU of 2lsc by Molmil
Solution structure of 2'F-ANA and ANA self-complementary duplex
Descriptor: DNA (5'-D(*(CFL)P*(GFL)P*(CFL)P*(GFL)P*(A5O)P*(A5O)P*(UAR)P*(UAR)P*(CFL)P*(GFL)P*(CFL)P*(GFL))-3')
Authors:Martin-Pintado, N, Yahyaee, M, Campos, R, Noronha, A, Wilds, C, Damha, M, Gonzalez, C.
Deposit date:2012-04-26
Release date:2012-07-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion.
Nucleic Acids Res., 40, 2012
5DQG
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BU of 5dqg by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dAMPNPP Opposite O4-Ethylthymidine
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-14
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DLG
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BU of 5dlg by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Methylhymidine
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5DB)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-04
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DQH
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BU of 5dqh by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Ethylthymidine
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-14
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DLF
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BU of 5dlf by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dATP Opposite O4-Methylhymidine
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-04
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DQI
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BU of 5dqi by Molmil
Crystal Structure of Human DNA Polymerase Eta Extending an O4-Ethylthymidine : dA Pair By Inserting dCTP Opposite dG
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*AP*C)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-14
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
2FIH
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BU of 2fih by Molmil
Crystal Structure Analysis of the B-DNA Dodecamer CGCGAA-aU-TCGCG, with Incorporated Arabino-Uridine (aU)
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*(UAR)P*TP*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Egli, M, Li, F.
Deposit date:2005-12-29
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2FII
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BU of 2fii by Molmil
Crystal Structure Analysis of the B-DNA Dodecamer CGCGAAT-aU-CGCG, with Incorporated Arabino-Uridin (aU)
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*(UAR)P*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Egli, M, Li, F.
Deposit date:2005-12-29
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2FIJ
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BU of 2fij by Molmil
Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-aU-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and Arabino-Uridine (aU)
Descriptor: 5'-D(*GP*CP*GP*TP*(A2M)P*(UAR)P*AP*CP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III)
Authors:Egli, M, Li, F.
Deposit date:2005-12-29
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2FIL
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BU of 2fil by Molmil
Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)
Descriptor: 5'-D(*GP*CP*GP*TP*(A2M)P*(TAF)P*AP*CP*GP*C)-3', COBALT HEXAMMINE(III)
Authors:Egli, M, Li, F.
Deposit date:2005-12-29
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2GUN
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BU of 2gun by Molmil
RNA-Binding Affinities and Crystal Structure of Oligonucleotides containing Five-Atom Amide-Based Backbone Structures
Descriptor: 5'-D(*TP*TP*CP*(T2T)P*(CBR)P*TP*TP*C)-3', 5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*A)-3', COBALT (III) ION, ...
Authors:Pallan, P.S, Egli, M.
Deposit date:2006-05-01
Release date:2006-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RNA-Binding Affinities and Crystal Structure of Oligonucleotides Containing Five-Atom Amide-Based Backbone Structures.
Biochemistry, 45, 2006
1FC8
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BU of 1fc8 by Molmil
NMR SOLUTION STRUCTURE OF A CHIMERIC OLIGONUCLEOTIDE HAIRPIN R(GGAC)D(TTCG)2'F-A(GTCC)
Descriptor: 5'-R(*GP*GP*AP*CP)D(*TP*TP*CP*GP*(GFL)P*(TAF)P*(CFL)P*(CFL))-3'
Authors:Trempe, J.-F, Gehring, K.
Deposit date:2000-07-18
Release date:2001-05-30
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes.
J.Am.Chem.Soc., 123, 2001

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