5YPO
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![BU of 5ypo by Molmil](/molmil-images/mine/5ypo) | Crystal structure of PSD-95 GK domain in complex with phospho-SAPAP peptide | Descriptor: | Disks large homolog 4, GLYCEROL, SAPAP | Authors: | Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhang, R, Zhang, M. | Deposit date: | 2017-11-02 | Release date: | 2018-03-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs. Cell Rep, 21, 2017
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5YPR
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![BU of 5ypr by Molmil](/molmil-images/mine/5ypr) | Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor | Descriptor: | Disks large homolog 4, Synthesized GK inhibitor | Authors: | Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhu, R, Zhang, M. | Deposit date: | 2017-11-02 | Release date: | 2018-03-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs. Cell Rep, 21, 2017
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7YOX
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![BU of 7yox by Molmil](/molmil-images/mine/7yox) | |
5ZYS
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![BU of 5zys by Molmil](/molmil-images/mine/5zys) | Structure of Nephrin/MAGI1 complex | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin | Authors: | Weng, Z.F, Shng, Y, Zhu, J.W, Zhang, R.G. | Deposit date: | 2018-05-28 | Release date: | 2019-01-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling. J. Am. Soc. Nephrol., 29, 2018
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6IE1
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![BU of 6ie1 by Molmil](/molmil-images/mine/6ie1) | Crystal Structure of ELMO2(Engulfment and cell motility protein 2) | Descriptor: | Engulfment and cell motility protein 2, GLYCEROL | Authors: | Weng, Z.F, Lin, L, Zhang, R.G, Zhu, J.W. | Deposit date: | 2018-09-12 | Release date: | 2019-01-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds Nat Commun, 10, 2019
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6IDX
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![BU of 6idx by Molmil](/molmil-images/mine/6idx) | Crystal Structure of BAI1/ELMO2 complex | Descriptor: | Adhesion G protein-coupled receptor B1, Engulfment and cell motility protein 2 | Authors: | Weng, Z.F, Lin, L, Zhu, J.W, Zhang, R.G. | Deposit date: | 2018-09-11 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds Nat Commun, 10, 2019
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7DKL
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5YBE
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![BU of 5ybe by Molmil](/molmil-images/mine/5ybe) | Structure of KANK1/KIF21A complex | Descriptor: | 1,2-ETHANEDIOL, KIF21A, Kank1 protein | Authors: | Weng, Z.F, Shang, Y, Yao, D.Q, Zhu, J.W, Zhang, R.G. | Deposit date: | 2017-09-04 | Release date: | 2017-11-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.111 Å) | Cite: | Structural analyses of key features in the KANK1/KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex. J. Biol. Chem., 293, 2018
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7W7P
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7C2E
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![BU of 7c2e by Molmil](/molmil-images/mine/7c2e) | GLP-1R-Gs complex structure with a small molecule full agonist | Descriptor: | 2-[[4-[6-[(4-cyano-2-fluoranyl-phenyl)methoxy]pyridin-2-yl]-3,6-dihydro-2~{H}-pyridin-1-yl]methyl]-3-[[(2~{S})-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Ma, H, Yuan, D.P, Huang, W, Wenge, Z, Xu, E. | Deposit date: | 2020-05-07 | Release date: | 2020-08-26 | Last modified: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural insights into the activation of GLP-1R by a small molecule agonist. Cell Res., 30, 2020
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6OQA
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![BU of 6oqa by Molmil](/molmil-images/mine/6oqa) | Crystal structure of CEP250 bound to FKBP12 in the presence of FK506-like novel natural product | Descriptor: | (3R,4E,7E,10R,11S,12R,13S,16R,17R,24aS)-11,17-dihydroxy-10,12,16-trimethyl-3-[(2R)-1-phenylbutan-2-yl]-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1,4]oxazacyclohenicosine-1,18,19(21H)-trione, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | Authors: | Lee, S.-J, Shigdel, U.K, Townson, S.A, Verdine, G.L. | Deposit date: | 2019-04-26 | Release date: | 2020-04-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface. Proc.Natl.Acad.Sci.USA, 117, 2020
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4NUZ
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![BU of 4nuz by Molmil](/molmil-images/mine/4nuz) | Crystal structure of a glycosynthase mutant (D233Q) of EndoS, an endo-beta-N-acetyl-glucosaminidase from Streptococcus pyogenes | Descriptor: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase F2 | Authors: | Trastoy, B, Guenther, S, Snyder, G.A, Sundberg, E.J. | Deposit date: | 2013-12-04 | Release date: | 2014-04-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.905 Å) | Cite: | Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies. Proc.Natl.Acad.Sci.USA, 111, 2014
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4NUY
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![BU of 4nuy by Molmil](/molmil-images/mine/4nuy) | Crystal structure of EndoS, an endo-beta-N-acetyl-glucosaminidase from Streptococcus pyogenes | Descriptor: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase F2 | Authors: | Trastoy, B, Guenther, S, Snyder, G.A, Sundberg, E.J. | Deposit date: | 2013-12-04 | Release date: | 2014-04-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.609 Å) | Cite: | Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies. Proc.Natl.Acad.Sci.USA, 111, 2014
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5KZP
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4L3E
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3R8B
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![BU of 3r8b by Molmil](/molmil-images/mine/3r8b) | |