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5T47
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BU of 5t47 by Molmil
Crystal structure of the D. melanogaster eIF4E-eIF4G complex
Descriptor: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T46
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BU of 5t46 by Molmil
Crystal structure of the human eIF4E-eIF4G complex
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T48
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BU of 5t48 by Molmil
Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
4UEB
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BU of 4ueb by Molmil
Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form II)
Descriptor: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UE9
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BU of 4ue9 by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein 4E-T
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEA
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BU of 4uea by Molmil
Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form I)
Descriptor: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEC
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BU of 4uec by Molmil
Complex of D. melanogaster eIF4E with eIF4G and cap analog
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UED
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BU of 4ued by Molmil
Complex of human eIF4E with the 4E binding protein 4E-BP1
Descriptor: EUKARYOTIC TRANSLATION FACTOR 4E-BINDING PROTEIN 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UE8
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BU of 4ue8 by Molmil
Complex of D. melanogaster eIF4E with the 4E binding protein Thor
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 4E-BINDING PROTEIN THOR, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2014-12-16
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
5NVL
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BU of 5nvl by Molmil
Crystal structure of the human 4EHP-GIGYF2 complex
Descriptor: Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 2
Authors:Peter, D, Valkov, E.
Deposit date:2017-05-04
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017
5NVM
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BU of 5nvm by Molmil
Crystal structure of the human 4EHP-GIGYF2 complex lacking the auxiliary sequences
Descriptor: Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 2, PHOSPHATE ION
Authors:Peter, D, Valkov, E.
Deposit date:2017-05-04
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017
5NVN
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BU of 5nvn by Molmil
Crystal structure of the human 4EHP-4E-BP1 complex
Descriptor: Eukaryotic translation initiation factor 4E type 2, Eukaryotic translation initiation factor 4E-binding protein 1, FORMIC ACID
Authors:Peter, D, Sandmeir, F, Valkov, E.
Deposit date:2017-05-04
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017
5NVK
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BU of 5nvk by Molmil
Crystal structure of the human 4EHP-GIGYF1 complex
Descriptor: Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 1
Authors:Peter, D, Valkov, E.
Deposit date:2017-05-04
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017
6FC2
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BU of 6fc2 by Molmil
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae
Descriptor: CALCIUM ION, Eukaryotic translation initiation factor 4E, Protein EAP1
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FBZ
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BU of 6fbz by Molmil
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-like protein,Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.496 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC3
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BU of 6fc3 by Molmil
Crystal structure of the eIF4E-p20 complex from Saccharomyces cerevisiae
Descriptor: Cap-associated protein CAF20, Eukaryotic translation initiation factor 4E, GLYCEROL, ...
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC1
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BU of 6fc1 by Molmil
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae in the cap-bound state
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, GLYCEROL, ...
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC0
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BU of 6fc0 by Molmil
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum
Descriptor: Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.293 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
5ABV
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BU of 5abv by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GH11071P
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5ABY
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BU of 5aby by Molmil
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli
Descriptor: 4E-BINDING PROTEIN MEXTLI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-3, GLYCEROL, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5ABU
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BU of 5abu by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog
Descriptor: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, CHLORIDE ION, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5ABX
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BU of 5abx by Molmil
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli and cap analog
Descriptor: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
6S8R
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BU of 6s8r by Molmil
D. melanogaster RNA helicase Me31B in complex with GIGYF
Descriptor: ACETATE ION, ATP-dependent RNA helicase me31b, GIGYF family protein CG11148
Authors:Peter, D, Valkov, E.
Deposit date:2019-07-10
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
Genes Dev., 33, 2019
6S8S
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BU of 6s8s by Molmil
Extended structure of the human DDX6 C-terminal domain in complex with an EDC3 FDF peptide
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Enhancer of mRNA-decapping protein 3, PHOSPHATE ION, ...
Authors:Peter, D, Valkov, E.
Deposit date:2019-07-10
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
Genes Dev., 33, 2019
4JFN
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BU of 4jfn by Molmil
Crystal structure of the N-terminal, growth factor-like domain of the amyloid precursor protein bound to copper
Descriptor: Amyloid beta A4 protein, COPPER (II) ION, GLYCEROL
Authors:Wild, K, Baumkotter, F, Kins, S.
Deposit date:2013-02-28
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain
J.Neurosci., 34, 2014

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