6S8S

Extended structure of the human DDX6 C-terminal domain in complex with an EDC3 FDF peptide

Summary for 6S8S

Entry DOI	10.2210/pdb6s8s/pdb
Descriptor	Probable ATP-dependent RNA helicase DDX6, Enhancer of mRNA-decapping protein 3, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	translational control, mrna decay, mirna, rna binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	57051.50
Authors	Peter, D.,Valkov, E. (deposition date: 2019-07-10, release date: 2019-09-04, Last modification date: 2024-01-24)
Primary citation	Peter, D.,Ruscica, V.,Bawankar, P.,Weber, R.,Helms, S.,Valkov, E.,Igreja, C.,Izaurralde, E. Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression. Genes Dev., 33:1355-1360, 2019 Cited by PubMed: 31439631 DOI: 10.1101/gad.329219.119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.21 Å)

Structure validation