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8HY4
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Crystal structure of human transthyretin variant A97S at pH 7.6
分子名称: Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2023-01-05
公開日2023-05-03
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7YBR
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Crystal structure of human transthyretin variant A97S complexed with Tolcapone
分子名称: Tolcapone, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-06-29
公開日2023-05-03
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7YCQ
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Crystal structure of human transthyretin variant A97S complexed with Diflunisal
分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-07-01
公開日2023-05-03
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7Y6J
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Crystal structure of human transthyretin variant A97S at pH 5.4
分子名称: GLYCEROL, Transthyretin
著者Wang, Y.S, Huang, C.H, Tzeng, S.R.
登録日2022-06-20
公開日2023-05-03
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
6A4X
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Oxidase ChaP-H2
分子名称: Bleomycin resistance protein, FE (II) ION
著者Zhang, B, Wang, Y.S, Ge, H.M.
登録日2018-06-21
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
7W73
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Cryo-EM map of PEDV S protein with one protomer in the D0-up conformation while the other two in the D0-down conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2021-12-03
公開日2022-08-03
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
7W6M
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Cryo-EM map of PEDV (Pintung 52) S protein with all three protomers in the D0-down conformation determined in situ on intact viral particles.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2021-12-02
公開日2022-08-03
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
8KE2
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PylRS C-terminus domain mutant bound with L-3-trifluoromethylphenylalanine and AMPNP
分子名称: (2S)-2-azanyl-3-[3-(trifluoromethyl)phenyl]propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.19639969 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE4
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PylRS C-terminus domain mutant bound with D-3-bromophenylalanine and AMPNP
分子名称: (2R)-2-azanyl-3-(3-bromophenyl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75050962 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE3
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PylRS C-terminus domain mutant bound with D-3-trifluoromethylphenylalanine and AMPNP
分子名称: (2R)-2-azanyl-3-[3-(trifluoromethyl)phenyl]propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.89980984 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE6
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PylRS C-terminus domain mutant bound with L-3-chlorophenylalanine and AMPNP
分子名称: 3-CHLORO-L-PHENYLALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.89570856 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE1
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BU of 8ke1 by Molmil
PylRS C-terminus domain mutant bound with L-3-bromophenylalanine and AMPNP
分子名称: 3-bromo-L-phenylalanine, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.50081539 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
8KE5
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BU of 8ke5 by Molmil
PylRS C-terminus domain mutant bound with D-3-chlorophenylalanine and AMPNP
分子名称: (2R)-2-azanyl-3-(3-chlorophenyl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2023-08-11
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.900073 Å)
主引用文献Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
1OVQ
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BU of 1ovq by Molmil
Solution structure of the hypothetical protein YqgF from Escherichia coli
分子名称: Hypothetical protein yqgF
著者Liu, D, Wang, Y.S, Wyss, D.F.
登録日2003-03-27
公開日2003-11-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the hypothetical protein YqgF from Escherichia coli reveals an RNAse H fold.
J.Biomol.NMR, 27, 2003
1ONB
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BU of 1onb by Molmil
Solution structure of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase
分子名称: helicase NS3
著者Liu, D, Wang, Y.S, Gesell, J.J, Wyss, D.F.
登録日2003-02-27
公開日2003-03-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase
J.Mol.Biol., 314, 2001
1JR6
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Solution Structure of an Engineered Arginine-rich Subdomain 2 of the Hepatitis C Virus NS3 RNA Helicase
分子名称: Helicase NS3
著者Liu, D, Wyss, D.F, Wang, Y.S, Gesell, J.J.
登録日2001-08-10
公開日2002-08-10
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase.
J.Mol.Biol., 314, 2001
4ZIB
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BU of 4zib by Molmil
Crystal Structure of the C-terminal domain of PylRS mutant bound with 3-benzothienyl-l-alanine and ATP
分子名称: 1,2-ETHANEDIOL, 3-(1-benzothiophen-3-yl)-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Nakamura, A, Guo, L.T, Wang, Y.S, Soll, D.
登録日2015-04-28
公開日2016-03-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.054 Å)
主引用文献Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog.
Nucleic Acids Res., 43, 2015
7Y6U
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Symmetry-expanded and locally refined protomer structure of IPEC-J2 cell-derived PEDV PT52 S with a CTD-close conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2022-06-21
公開日2022-08-03
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
7Y6V
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Symmetry-expanded and locally refined protomer structure of IPEC-J2 cell-derived PEDV PT52 S with a CTD-open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2022-06-21
公開日2022-08-03
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
7Y6S
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Cryo-EM map of IPEC-J2 cell-derived PEDV PT52 S protein with three D0-up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2022-06-21
公開日2022-08-03
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
7Y6T
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Cryo-EM map of IPEC-J2 cell-derived PEDV PT52 S protein one D0-down and two D0-up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2022-06-21
公開日2022-08-03
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
Nat Commun, 13, 2022
7WCC
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Oxidase ChaP-D49L/Q91C mutant
分子名称: ChaP, FE (III) ION
著者Sun, M.X, Zheng, W, Wang, Y.S, Zhu, J.P, Tan, R.X.
登録日2021-12-19
公開日2023-05-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Oxidase ChaP-D49L/Q91C mutant
To Be Published
6LY6
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PylRS C-terminus domain mutant bound with 3-(1-Naphthyl)-L-alanine and AMPNP
分子名称: MAGNESIUM ION, NAPHTHALEN-2-YL-3-ALANINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2020-02-13
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5001328 Å)
主引用文献Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
6LY3
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PylRS C-terminus domain mutant bound with 3-Benzothienyl-L-alanine and AMPNP
分子名称: 3-(1-benzothiophen-3-yl)-L-alanine, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2020-02-13
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.89590144 Å)
主引用文献Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
6LYA
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PylRS C-terminus domain mutant bound with 1-Methyl-L-tryptophan and AMPNP
分子名称: 1,2-ETHANEDIOL, 1-Methyl-L-tryptophan, MAGNESIUM ION, ...
著者Weng, J.H, Tsai, M.D, Wang, Y.S.
登録日2020-02-13
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.590702 Å)
主引用文献Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020

 

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