8HY4

Crystal structure of human transthyretin variant A97S at pH 7.6

Summary for 8HY4

• Entry DOI: 10.2210/pdb8hy4/pdb
• Descriptor: Transthyretin (2 entities in total)
• Functional Keywords: transport thyroxine, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 29991.42

Authors

Wang, Y.S.,Huang, C.H.,Tzeng, S.R. (deposition date: 2023-01-05, release date: 2023-05-03)

• Primary citation: Wang, Y.S.,Huang, C.H.,Liou, G.G.,Hsueh, H.W.,Liang, C.T.,Tseng, H.C.,Huang, S.J.,Chao, C.C.,Hsieh, S.T.,Tzeng, S.R.; A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.; Protein Sci., 32:e4610-e4610, 2023; PubMed: 36851846; DOI: 10.1002/pro.4610

Experimental method

X-RAY DIFFRACTION (1.53 Å)