8HY4

Crystal structure of human transthyretin variant A97S at pH 7.6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transthyretin	polymer	136	14995.7	2	UniProt (P02766) Pfam (PF00576)	Homo sapiens (human)	ATTR,Prealbumin,TBPA
2	C, D (A, B)	water	water		18.0	138	Chemie (HOH)

Sequence modifications

A, B: 1 - 127 (UniProt: P02766)

PDB	External Database	Details
Met 0	-	initiating methionine
Ser 97	Ala 117	engineered mutation
Leu 128	-	expression tag
Glu 129	-	expression tag
His 130	-	expression tag
His 131	-	expression tag
His 132	-	expression tag
His 133	-	expression tag
His 134	-	expression tag
His 135	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29991.4
All*	Total formula weight	29991.4

*Water molecules are not included.