Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8ZPV
DownloadVisualize
BU of 8zpv by Molmil
Nipah virus polymerase complex
Descriptor: Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION
Authors:Wang, Y.R, Zhang, H.Q.
Deposit date:2024-05-31
Release date:2024-11-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of polymerase complex
Sci Adv, 2024
5GWI
DownloadVisualize
BU of 5gwi by Molmil
Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873R
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.737 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
5GWK
DownloadVisualize
BU of 5gwk by Molmil
Human topoisomerase IIalpha in complex with DNA and etoposide
Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wang, Y.R, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.152 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
5GWJ
DownloadVisualize
BU of 5gwj by Molmil
Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873S
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.566 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
2ZED
DownloadVisualize
BU of 2zed by Molmil
Crystal structure of the human glutaminyl cyclase mutant S160A at 1.7 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-12
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEH
DownloadVisualize
BU of 2zeh by Molmil
Crystal structure of the human glutaminyl cyclase mutant E201Q at 1.8 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-12
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEE
DownloadVisualize
BU of 2zee by Molmil
Crystal structure of the human glutaminyl cyclase mutant S160G at 1.99 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-12
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEL
DownloadVisualize
BU of 2zel by Molmil
Crystal structure of the human glutaminyl cyclase mutant D248A at 1.97 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-13
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEF
DownloadVisualize
BU of 2zef by Molmil
Crystal structure of the human glutaminyl cyclase mutant E201D at 1.67 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-12
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEG
DownloadVisualize
BU of 2zeg by Molmil
Crystal structure of the human glutaminyl cyclase mutant E201L at 2.08 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, IMIDAZOLE, SULFATE ION, ...
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-12
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEO
DownloadVisualize
BU of 2zeo by Molmil
Crystal structure of the human glutaminyl cyclase mutant D305E at 1.66 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-13
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEN
DownloadVisualize
BU of 2zen by Molmil
Crystal structure of the human glutaminyl cyclase mutant D305A at 1.78 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-13
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEP
DownloadVisualize
BU of 2zep by Molmil
Crystal structure of the human glutaminyl cyclase mutant H319L at 2.1 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-13
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
2ZEM
DownloadVisualize
BU of 2zem by Molmil
Crystal structure of the human glutaminyl cyclase mutant D248Q at 2.18 angstrom resolution
Descriptor: Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION
Authors:Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H.
Deposit date:2007-12-13
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
5ZRF
DownloadVisualize
BU of 5zrf by Molmil
Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA and etoposide in space group p21
Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA topoisomerase 2-beta, ...
Authors:Chen, S.F, Wang, Y.R, Wu, C.C, Chan, N.L.
Deposit date:2018-04-24
Release date:2018-08-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.
Nat Commun, 9, 2018
5ZEN
DownloadVisualize
BU of 5zen by Molmil
Crystal structure of human topoisomerase II beta in complex with DNA: a new quaternary conformation showing opening of the protein-linked DNA-gate
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Chen, S.F, Wang, Y.R, Chan, N.L.
Deposit date:2018-02-27
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.
Nat Commun, 9, 2018
5ZQF
DownloadVisualize
BU of 5zqf by Molmil
Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA in space group P3221
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA topoisomerase 2-beta, DNA/RNA (5'-D(P*AP*GP*C)-R(P*(IU))-D(P*CP*GP*GP*C)-R(P*(IU))-3'), ...
Authors:Chen, S.F, Wang, Y.R, Chan, N.L.
Deposit date:2018-04-18
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.873 Å)
Cite:Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.
Nat Commun, 9, 2018
5FWP
DownloadVisualize
BU of 5fwp by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
Authors:Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
Deposit date:2016-02-18
Release date:2016-10-26
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
4J3N
DownloadVisualize
BU of 4j3n by Molmil
Human Topoisomerase Iibeta in complex with DNA
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
Deposit date:2013-02-06
Release date:2013-10-02
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
4G0W
DownloadVisualize
BU of 4g0w by Molmil
Human topoisomerase iibeta in complex with DNA and ametantrone
Descriptor: 1,4-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
Deposit date:2012-07-10
Release date:2013-07-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.696 Å)
Cite:On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
4G0U
DownloadVisualize
BU of 4g0u by Molmil
Human topoisomerase IIbeta in complex with DNA and amsacrine
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
Deposit date:2012-07-10
Release date:2013-07-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
4G0V
DownloadVisualize
BU of 4g0v by Molmil
Human topoisomerase iibeta in complex with DNA and mitoxantrone
Descriptor: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
Deposit date:2012-07-10
Release date:2013-07-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.548 Å)
Cite:On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
7RS5
DownloadVisualize
BU of 7rs5 by Molmil
Cryo-EM structure of Kip3 (AMPPNP) bound to Taxol-Stabilized Microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Hernandez-Lopez, R.A, Leschziner, A.E, Arellano-Santoyo, H, Pellman, D, Stokasimov, E, Wang, R.Y.-R.
Deposit date:2021-08-10
Release date:2022-08-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization
Biorxiv, 2021
5FWM
DownloadVisualize
BU of 5fwm by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
Authors:Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
Deposit date:2016-02-18
Release date:2016-07-06
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
5WP9
DownloadVisualize
BU of 5wp9 by Molmil
Structural Basis of Mitochondrial Receptor Binding and Constriction by Dynamin-Related Protein 1
Descriptor: Dynamin-1-like protein, MAGNESIUM ION, Mitochondrial dynamics protein MID49, ...
Authors:Kalia, R, Wang, R.Y.R, Yusuf, A, Thomas, P.V, Agard, D.A, Shaw, J.M, Frost, A.
Deposit date:2017-08-03
Release date:2018-06-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.22 Å)
Cite:Structural basis of mitochondrial receptor binding and constriction by DRP1.
Nature, 558, 2018

 

12>

229183

PDB entries from 2024-12-18

PDB statisticsPDBj update infoContact PDBjnumon