2LKT
 
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6K5E
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6KG7
 | | Cryo-EM Structure of the Mammalian Tactile Channel Piezo2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Piezo-type mechanosensitive ion channel component 2 | | 著者 | Wang, L, Zhou, H, Zhang, M, Liu, W, Deng, T, Zhao, Q, Li, Y, Lei, J, Li, X, Xiao, B. | | 登録日 | 2019-07-11 | | 公開日 | 2019-09-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure and mechanogating of the mammalian tactile channel PIEZO2.
Nature, 573, 2019
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6L3E
 | | Crystal structure of Salmonella enterica sugar-binding protein MalE | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | | 著者 | Wang, L, Chen, Y, Liu, W, Lan, J, Shang, F, Xu, Y. | | 登録日 | 2019-10-10 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of Salmonella enterica sugar-binding protein MalE
To Be Published
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6L0Z
 | | The crystal structure of Salmonella enterica sugar-binding protein MalE | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,5-anhydro-D-glucitol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Wang, L, Chen, Y, Liu, W, Lan, J, Shang, F, Xu, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of Salmonella enterica sugar-binding protein MalE
To Be Published
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6L19
 | | The crystal structure of competence or damage-inducible protein from Enterobacter asburiae | | 分子名称: | CHLORIDE ION, GLYCEROL, PncC family amidohydrolase, ... | | 著者 | Wang, L, Chen, Y, Liu, W, Lan, J, Shang, F, Xu, Y. | | 登録日 | 2019-09-28 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | The crystal structure of Competence or damage-inducible protein from Enterobacter asburiae
To Be Published
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6MJ2
 | | Human TRPM2 ion channel in a calcium- and ADPR-bound state | | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily M member 2 | | 著者 | Wang, L, Fu, T.M, Xia, S, Wu, H. | | 登録日 | 2018-09-20 | | 公開日 | 2018-12-12 | | 最終更新日 | 2019-01-02 | | 実験手法 | ELECTRON MICROSCOPY (6.36 Å) | | 主引用文献 | Structures and gating mechanism of human TRPM2.
Science, 362, 2018
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6MIX
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6MIZ
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7ZYU
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2OA4
 | | Solution NMR Structure: Northeast Structural Genomics Consortium Target SiR5 | | 分子名称: | SiR5 | | 著者 | Wang, L, Rossi, P, Chen, C.X, Nwosu, C, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Burkhard, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-12-14 | | 公開日 | 2007-03-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Northeast Structural Genomics Consortium Target SiR5
To be Published
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2OT2
 | | Solution Structure of HypC | | 分子名称: | Hydrogenase isoenzymes formation protein hypC | | 著者 | Wang, L, Jin, C. | | 登録日 | 2007-02-07 | | 公開日 | 2007-09-04 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Escherichia coli HypC
Biochem.Biophys.Res.Commun., 361, 2007
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7FFT
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7FFW
 | | The crystal structure of a domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, METHOXYETHANE, ... | | 著者 | Wang, L, Bu, T, Bai, X. | | 登録日 | 2021-07-23 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-05-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of the domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica.
Acta Crystallogr D Struct Biol, 78, 2022
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7EPU
 | | Crystal structure of HsALC1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromodomain-helicase-DNA-binding protein 1-like, MAGNESIUM ION, ... | | 著者 | Wang, L, Chen, K.J. | | 登録日 | 2021-04-27 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021
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7F8E
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4V9C
 | | Allosteric control of the ribosome by small-molecule antibiotics | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Cate, J.H.D, Pulk, A, Blanchard, S.C, Wang, L, Feldman, M.B, Wasserman, M.R, Altman, R. | | 登録日 | 2012-07-25 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Allosteric control of the ribosome by small-molecule antibiotics.
Nat.Struct.Mol.Biol., 19, 2012
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6ND0
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2PVX
 | | NMR and X-ray Analysis of Structural Additivity in Metal Binding Site-Swapped Hybrids of Rubredoxin | | 分子名称: | Rubredoxin, ZINC ION | | 著者 | Wang, L, LeMaster, D.M, Hernandez, G, Li, H. | | 登録日 | 2007-05-10 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin
Bmc Struct.Biol., 7, 2007
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3TG5
 | | Structure of SMYD2 in complex with p53 and SAH | | 分子名称: | Cellular tumor antigen p53, GLYCEROL, N-lysine methyltransferase SMYD2, ... | | 著者 | Zhao, K, Wang, L. | | 登録日 | 2011-08-17 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
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3TG4
 | | Structure of SMYD2 in complex with SAM | | 分子名称: | GLYCEROL, N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ... | | 著者 | Zhao, K, Wang, L. | | 登録日 | 2011-08-17 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
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7TAI
 | | Structure of STEAP2 in complex with ligands | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Wang, L, Chen, K.H, Zhou, M. | | 登録日 | 2021-12-20 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2.
Elife, 12, 2023
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7TRJ
 | | The eukaryotic translation initiation factor 2B from Homo sapiens with a H160D mutation in the beta subunit | | 分子名称: | Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... | | 著者 | Wang, L, Schoof, M, Lawrence, R, Boone, M, Frost, A, Walter, P. | | 登録日 | 2022-01-29 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation.
Elife, 11, 2022
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4U7P
 | | Crystal structure of DNMT3A-DNMT3L complex | | 分子名称: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y. | | 登録日 | 2014-07-31 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.821 Å) | | 主引用文献 | Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
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4X67
 | | Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions. | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Wang, L, Chong, J, Wang, D. | | 登録日 | 2014-12-07 | | 公開日 | 2015-02-04 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.
Proc.Natl.Acad.Sci.USA, 112, 2015
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