1NFK
 
 | | STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER | | 分子名称: | DNA (5'-D(*TP*GP*GP*GP*AP*AP*TP*TP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB)) | | 著者 | Ghosh, G, Van Duyne, G, Ghosh, S, Sigler, P.B. | | 登録日 | 1995-02-28 | | 公開日 | 1996-12-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of NF-kappa B p50 homodimer bound to a kappa B site.
Nature, 373, 1995
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5J0N
 | | Lambda excision HJ intermediate | | 分子名称: | Excisionase, Integrase, Integration host factor subunit alpha, ... | | 著者 | Van Duyne, G, Grigorieff, N, Landy, A. | | 登録日 | 2016-03-28 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (11 Å) | | 主引用文献 | Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.
Elife, 5, 2016
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6VRG
 | | Structure of HIV-1 integrase with native amino-terminal sequence | | 分子名称: | Integrase, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Eilers, G, Gupta, K, Allen, A, Zhou, J, Hwang, Y, Cory, M, Bushman, F.D, Van Duyne, G.D. | | 登録日 | 2020-02-07 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Influence of the amino-terminal sequence on the structure and function of HIV integrase.
Retrovirology, 17, 2020
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8CT5
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8CTA
 | | Minimal 2:2 Ternary Complex between BI-224436 bound HIV-1 Integrase Catalytic Core Domain Dimer and Carboxy Terminal Domains | | 分子名称: | (2S)-tert-butoxy[4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl]acetic acid, 1,2-ETHANEDIOL, Integrase | | 著者 | Gupta, K, Van Duyne, G.D, Eilers, G, Bushman, F.D. | | 登録日 | 2022-05-13 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 angstrom resolution: Routes to inhibitor optimization.
Plos Pathog., 19, 2023
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8CT7
 | | Catalytic Core Domain of HIV-1 Integrase (F185K) bound with BI-224436 | | 分子名称: | (2S)-tert-butoxy[4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl]acetic acid, 1,2-ETHANEDIOL, Integrase, ... | | 著者 | Gupta, K, Van Duyne, G.D, Eilers, G, Bushman, F.D. | | 登録日 | 2022-05-13 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 angstrom resolution: Routes to inhibitor optimization.
Plos Pathog., 19, 2023
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4OJR
 | | Crystal Structure of the HIV-1 Integrase catalytic domain with GSK1264 | | 分子名称: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, CACODYLATE ION, HIV-1 Integrase, ... | | 著者 | Gupta, K, Brady, T, Dyer, B, Hwang, Y, Male, F, Nolte, R.T, Wang, L, Velthuisen, E, Jeffrey, J, Van Duyne, G, Bushman, F.D. | | 登録日 | 2014-01-21 | | 公開日 | 2014-06-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Allosteric Inhibition of Human Immunodeficiency Virus Integrase: LATE BLOCK DURING VIRAL REPLICATION AND ABNORMAL MULTIMERIZATION INVOLVING SPECIFIC PROTEIN DOMAINS.
J.Biol.Chem., 289, 2014
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1BFS
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1BFT
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2LEH
 | | Solution structure of the core SMN-Gemin2 complex | | 分子名称: | Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1 | | 著者 | Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G. | | 登録日 | 2011-06-15 | | 公開日 | 2012-06-27 | | 最終更新日 | 2021-08-18 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the core SMN-Gemin2 complex.
Biochem.J., 445, 2012
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