8CT5
Catalytic Core Domain of HIV-1 Integrase (F185K)
Summary for 8CT5
| Entry DOI | 10.2210/pdb8ct5/pdb |
| Descriptor | Integrase, SULFATE ION (3 entities in total) |
| Functional Keywords | viral dna integration, dna binding, ledgf binding, viral protein |
| Biological source | Human immunodeficiency virus 1 |
| Total number of polymer chains | 1 |
| Total formula weight | 18278.40 |
| Authors | Gupta, K.,Van Duyne, G.D.,Eilers, G. (deposition date: 2022-05-13, release date: 2023-02-15, Last modification date: 2023-10-25) |
| Primary citation | Eilers, G.,Gupta, K.,Allen, A.,Montermoso, S.,Murali, H.,Sharp, R.,Hwang, Y.,Bushman, F.D.,Van Duyne, G. Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 angstrom resolution: Routes to inhibitor optimization. Plos Pathog., 19:e1011097-e1011097, 2023 Cited by PubMed: 36867659DOI: 10.1371/journal.ppat.1011097 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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