5EVY
 
 | | Salicylate hydroxylase substrate complex | | 分子名称: | 2-HYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Salicylate hydroxylase | | 著者 | Morimoto, Y, Uemura, T. | | 登録日 | 2015-11-20 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | The catalytic mechanism of decarboxylative hydroxylation of salicylate hydroxylase revealed by crystal structure analysis at 2.5 angstrom resolution
Biochem.Biophys.Res.Commun., 469, 2016
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7FCI
 | | human NTCP in complex with YN69083 Fab | | 分子名称: | Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter | | 著者 | Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y. | | 登録日 | 2021-07-14 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into the HBV receptor and bile acid transporter NTCP.
Nature, 606, 2022
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4Y61
 | | Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta, SLIT and NTRK-like protein 2 | | 著者 | Yamgata, A, Sato, Y, Goto-Ito, S, Uemura, T, Maeda, A, Shiroshima, T, Yoshida, T, Fukai, S. | | 登録日 | 2015-02-12 | | 公開日 | 2015-06-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.358 Å) | | 主引用文献 | Structure of Slitrk2-PTP delta complex reveals mechanisms for splicing-dependent trans-synaptic adhesion.
Sci Rep, 5, 2015
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5XWU
 | | Crystal structure of PTPdelta Ig1-Ig3 in complex with SALM2 LRR-Ig | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S. | | 登録日 | 2017-06-30 | | 公開日 | 2018-06-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.162 Å) | | 主引用文献 | Structural basis of trans-synaptic interactions between PTP delta and SALMs for inducing synapse formation.
Nat Commun, 9, 2018
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6JOD
 | | Angiotensin II type 2 receptor with ligand | | 分子名称: | Angiotensin II, Heavy chain of 4A03Fab, Light chain of 4A03Fab, ... | | 著者 | Asada, H, Iwata, S, Hirata, K, Shimamura, T. | | 登録日 | 2019-03-20 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone.
Structure, 28, 2020
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6LBH
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4ZY3
 | | Crystal Structure of Keap1 in Complex with a small chemical compound, K67 | | 分子名称: | FORMIC ACID, Kelch-like ECH-associated protein 1, N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide) | | 著者 | Fukutomi, T, Iso, T, Suzuki, T, Takagi, K, Mizushima, T, Komatsu, M, Yamamoto, M. | | 登録日 | 2015-05-21 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
Nat Commun, 7, 2016
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6KS2
 | | Structure of anti-Ghrelin receptor antibody | | 分子名称: | Fab7881 Heavy Chain (FabH), Fab7881 Light Chain (FabL) | | 著者 | Shiimura, Y, Horita, S, Asada, H, Hirata, K, Iwata, S, Kojima, M. | | 登録日 | 2019-08-23 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.753 Å) | | 主引用文献 | Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.
Nat Commun, 11, 2020
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6KO5
 | | Complex structure of Ghrelin receptor with Fab | | 分子名称: | 6-(4-bromanyl-2-fluoranyl-phenoxy)-2-methyl-3-[[(3~{S})-1-propan-2-ylpiperidin-3-yl]methyl]pyrido[3,2-d]pyrimidin-4-one, Chimera of Soluble cytochrome b562 and Growth hormone secretagogue receptor type 1, Fab7881 Heavy Chain, ... | | 著者 | Shiimura, Y, Horita, S, Asada, H, Hirata, K, Iwata, S, Kojima, M. | | 登録日 | 2019-08-08 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.
Nat Commun, 11, 2020
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7CEE
 | | Crystal structure of mouse neuroligin-3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-3 | | 著者 | Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S. | | 登録日 | 2020-06-23 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.763 Å) | | 主引用文献 | Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
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7CEG
 | | Crystal structure of the complex between mouse PTP delta and neuroligin-3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3 | | 著者 | Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S. | | 登録日 | 2020-06-23 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
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7DFP
 | | Human dopamine D2 receptor in complex with spiperone | | 分子名称: | 8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, D(2) dopamine receptor,Soluble cytochrome b562, FabH, ... | | 著者 | Im, D, Shimamura, T, Iwata, S. | | 登録日 | 2020-11-09 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the dopamine D 2 receptor in complex with the antipsychotic drug spiperone.
Nat Commun, 11, 2020
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8HRX
 | | Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex | | 分子名称: | Fab heavy chain from antibody IgG clone number YN9048, Fab light chain from antibody IgG clone number YN9048, PreS1 protein (Fragment), ... | | 著者 | Asami, J, Shimizu, T, Ohto, U. | | 登録日 | 2022-12-16 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structural basis of hepatitis B virus receptor binding.
Nat.Struct.Mol.Biol., 31, 2024
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8HRY
 | | Cryo-EM structure of human NTCP-myr-preS1-YN9016Fab complex | | 分子名称: | Fab heavy chain from antibody IgG clone number YN9016, Fab light chain from antibody IgG clone number YN9016, Large S protein (Fragment), ... | | 著者 | Asami, J, Shimizu, T, Ohto, U. | | 登録日 | 2022-12-16 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Structural basis of hepatitis B virus receptor binding.
Nat.Struct.Mol.Biol., 31, 2024
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4YFE
 | | Crystal structure of PTP delta Fn1-Fn2 | | 分子名称: | Receptor-type tyrosine-protein phosphatase delta | | 著者 | Yamagata, A, Fukai, S. | | 登録日 | 2015-02-25 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.972 Å) | | 主引用文献 | Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
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4YH6
 | | Crystal structure of IL1RAPL1 ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yamagata, A, Fukai, S. | | 登録日 | 2015-02-27 | | 公開日 | 2015-05-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
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4YFD
 | | Crystal structure PTP delta Ig1-Fn2 in complex with IL-1RAcP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein, Receptor-type tyrosine-protein phosphatase delta | | 著者 | Yamagata, A, Fukai, S. | | 登録日 | 2015-02-25 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.253 Å) | | 主引用文献 | Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
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4YH7
 | | Crystal structure of PTPdelta ectodomain in complex with IL1RAPL1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ... | | 著者 | Yamagata, A, Fukai, S. | | 登録日 | 2015-02-27 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | | 主引用文献 | Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
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4YFG
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5Z8X
 | | Crystal structure of human LRRTM2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat transmembrane neuronal protein 2 | | 著者 | Yamagata, A, Fukai, S. | | 登録日 | 2018-02-01 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Nat Commun, 9, 2018
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5XJM
 | | Complex structure of angiotensin II type 2 receptor with Fab | | 分子名称: | FabH, FabL, Sar1, ... | | 著者 | Asada, H, Horita, S, Shimamura, T, Iwata, S. | | 登録日 | 2017-05-02 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog
Nat. Struct. Mol. Biol., 25, 2018
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5Z8Y
 | | Crystal structure of human LRRTM2 in complex with Neurexin 1beta | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Yamagata, A, Fukai, S. | | 登録日 | 2018-02-01 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Nat Commun, 9, 2018
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5XLI
 | | Structure of anti-Angiotensin II type2 receptor antibody (D5711-4A03) | | 分子名称: | FabH, FabL | | 著者 | Asada, H, Horita, S, Iwata, S, Hirata, K. | | 登録日 | 2017-05-10 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog.
Nat. Struct. Mol. Biol., 25, 2018
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5XWS
 | | Crystal structure of SALM5 LRR-Ig | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat and fibronectin type-III domain-containing protein 5 | | 著者 | Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S. | | 登録日 | 2017-06-30 | | 公開日 | 2018-06-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.084 Å) | | 主引用文献 | Structural basis of trans-synaptic interactions between PTP delta and SALMs for inducing synapse formation.
Nat Commun, 9, 2018
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5XWT
 | | Crystal structure of PTPdelta Ig1-Fn1 in complex with SALM5 LRR-Ig | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S. | | 登録日 | 2017-06-30 | | 公開日 | 2018-06-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (4.178 Å) | | 主引用文献 | Structural basis of trans-synaptic interactions between PTP delta and SALMs for inducing synapse formation.
Nat Commun, 9, 2018
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