5XWU

Crystal structure of PTPdelta Ig1-Ig3 in complex with SALM2 LRR-Ig

Summary for 5XWU

Entry DOI	10.2210/pdb5xwu/pdb
Descriptor	Receptor-type tyrosine-protein phosphatase delta, Leucine-rich repeat and fibronectin type III domain-containing protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	synaptic orgnizers, cell adhesion
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	151924.35
Authors	Goto-Ito, S.,Yamagata, A.,Sato, Y.,Fukai, S. (deposition date: 2017-06-30, release date: 2018-06-06, Last modification date: 2020-07-29)
Primary citation	Goto-Ito, S.,Yamagata, A.,Sato, Y.,Uemura, T.,Shiroshima, T.,Maeda, A.,Imai, A.,Mori, H.,Yoshida, T.,Fukai, S. Structural basis of trans-synaptic interactions between PTP delta and SALMs for inducing synapse formation. Nat Commun, 9:269-269, 2018 Cited by PubMed: 29348429 DOI: 10.1038/s41467-017-02417-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.162 Å)

Structure validation