5XWU

Crystal structure of PTPdelta Ig1-Ig3 in complex with SALM2 LRR-Ig

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Receptor-type tyrosine-protein phosphatase delta	polymer	313	34433.0	2	UniProt (Q64487) Pfam (PF07679) Pfam (PF13927)	Mus musculus (Mouse)	R-PTP-delta
2	B, D (B, D)	Leucine-rich repeat and fibronectin type III domain-containing protein 1	polymer	365	40254.9	2	UniProt (Q2WF71) Pfam (PF13855) Pfam (PF07679)	Mus musculus (Mouse)	Synaptic adhesion-like molecule 2,Synaptic differentiation-enhancing molecule 1
3	E, F, G (E, F, G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	H, J, K, L (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5	I, M (A, C)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)

Sequence modifications

A, C: 27 - 328 (UniProt: Q64487)

PDB	External Database	Details
Leu 22	-	expression tag
Met 23	-	expression tag
Gly 24	-	expression tag
Cys 25	-	expression tag
Val 26	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag

B, D: 32 - 390 (UniProt: Q2WF71)

PDB	External Database	Details
His 391	-	expression tag
His 392	-	expression tag
His 393	-	expression tag
His 394	-	expression tag
His 395	-	expression tag
His 396	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	149375.8
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1275.3
All*	Total formula weight	151924.4

*Water molecules are not included.