6KO5

Complex structure of Ghrelin receptor with Fab

Summary for 6KO5

• Entry DOI: 10.2210/pdb6ko5/pdb
• Descriptor: Chimera of Soluble cytochrome b562 and Growth hormone secretagogue receptor type 1, Fab7881 Heavy Chain, Fab7881 Light Chain, ... (4 entities in total)
• Functional Keywords: g-protein coupled receptor, ghrelin, antagonist-bound complex, membrane protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 3
• Total formula weight: 95989.29

Authors

Shiimura, Y.,Horita, S.,Asada, H.,Hirata, K.,Iwata, S.,Kojima, M. (deposition date: 2019-08-08, release date: 2020-08-12, Last modification date: 2023-11-22)

• Primary citation: Shiimura, Y.,Horita, S.,Hamamoto, A.,Asada, H.,Hirata, K.,Tanaka, M.,Mori, K.,Uemura, T.,Kobayashi, T.,Iwata, S.,Kojima, M.; Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.; Nat Commun, 11:4160-4160, 2020; PubMed: 32814772; DOI: 10.1038/s41467-020-17554-1

Experimental method

X-RAY DIFFRACTION (3.3 Å)