6MYJ
| Pleurotus ostreatus OstreolysinA plus sphingomyelin | Descriptor: | 1,2-ETHANEDIOL, N-[(2S)-1-hydroxypropan-2-yl]butanamide, Ostreolysin A6, ... | Authors: | Tomchick, D.R, Radhakrishnan, A, Endapally, S. | Deposit date: | 2018-11-01 | Release date: | 2019-02-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes. Cell, 176, 2019
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6MYI
| Pleurotus ostreatus OstreolysinA | Descriptor: | 1,2-ETHANEDIOL, Ostreolysin A6, SODIUM ION | Authors: | Tomchick, D.R, Radhakrishnan, A, Endapally, S. | Deposit date: | 2018-11-01 | Release date: | 2019-02-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes. Cell, 176, 2019
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6N1Z
| Importin-9 bound to H2A-H2B | Descriptor: | Histone H2A, Histone H2B 1.1, Importin-9 | Authors: | Tomchick, D.R, Chook, Y.M, Padavannil, A. | Deposit date: | 2018-11-12 | Release date: | 2019-03-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone. Elife, 8, 2019
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6VVC
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6VVD
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6VVE
| Legionella pneumophila Lpg2603 kinase bound to IP6, Mn2+, and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Dot/Icm T4SS effector, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Tomchick, D.R, Tagliabracci, V.S, Park, B.C. | Deposit date: | 2020-02-17 | Release date: | 2020-04-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | ALegionellaeffector kinase is activated by host inositol hexakisphosphate. J.Biol.Chem., 295, 2020
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5EW4
| Crystal structure of C9ORF72 Antisense CCCCGG repeat RNA associated with Lou Gehrig's disease and frontotemporal dementia, crystallized with Sr2+ | Descriptor: | CHLORIDE ION, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Tomchick, D.R, Dodd, D.W, Gagnon, K.T, Corey, D.R. | Deposit date: | 2015-11-20 | Release date: | 2016-02-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches. Biochemistry, 55, 2016
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5EW7
| Crystal structure of C9ORF72 Antisense CCCCGG repeat RNA associated with Lou Gehrig's disease and frontotemporal dementia, crystallized with Ba2+ | Descriptor: | BARIUM ION, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Tomchick, D.R, Dodd, D.W, Gagnon, K.T, Corey, D.R. | Deposit date: | 2015-11-20 | Release date: | 2016-02-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches. Biochemistry, 55, 2016
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3BNE
| Lipoxygenase-1 (Soybean) I553A Mutant | Descriptor: | FE (III) ION, Seed lipoxygenase-1 | Authors: | Tomchick, D.R. | Deposit date: | 2007-12-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BNB
| Lipoxygenase-1 (Soybean) I553L Mutant | Descriptor: | FE (III) ION, Seed lipoxygenase-1 | Authors: | Tomchick, D.R. | Deposit date: | 2007-12-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BND
| Lipoxygenase-1 (Soybean), I553V Mutant | Descriptor: | FE (III) ION, Seed lipoxygenase-1 | Authors: | Tomchick, D.R. | Deposit date: | 2007-12-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BNC
| Lipoxygenase-1 (Soybean) I553G Mutant | Descriptor: | ACETIC ACID, FE (III) ION, Seed lipoxygenase-1 | Authors: | Tomchick, D.R. | Deposit date: | 2007-12-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1. Proc.Natl.Acad.Sci.Usa, 105, 2008
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5UF7
| CRYSTAL STRUCTURE OF MUNC13-1 MUN DOMAIN | Descriptor: | Protein unc-13 homolog A | Authors: | Tomchick, D.R, Rizo, J, Xu, J. | Deposit date: | 2017-01-03 | Release date: | 2017-02-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.896 Å) | Cite: | Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN. Elife, 6, 2017
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5UE8
| The crystal structure of Munc13-1 C1C2BMUN domain | Descriptor: | CHLORIDE ION, Protein unc-13 homolog A, ZINC ION | Authors: | Tomchick, D.R, Rizo, J, Xu, J. | Deposit date: | 2016-12-29 | Release date: | 2017-02-15 | Last modified: | 2018-03-28 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN. Elife, 6, 2017
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4M63
| Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Tomchick, D.R, Zahm, J.A, Rosen, M.K. | Deposit date: | 2013-08-08 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.748 Å) | Cite: | The Bacterial Effector VopL Organizes Actin into Filament-like Structures. Cell(Cambridge,Mass.), 155, 2013
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3L15
| Human Tead2 transcriptional factor | Descriptor: | GLYCEROL, Transcriptional enhancer factor TEF-4 | Authors: | Tomchick, D.R, Luo, X, Tian, W. | Deposit date: | 2009-12-10 | Release date: | 2010-04-07 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KY9
| Autoinhibited Vav1 | Descriptor: | Proto-oncogene vav, ZINC ION | Authors: | Tomchick, D.R, Rosen, M.K, Machius, M, Yu, B. | Deposit date: | 2009-12-04 | Release date: | 2010-02-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.731 Å) | Cite: | Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1 Cell(Cambridge,Mass.), 140, 2010
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3N5A
| Synaptotagmin-7, C2B-domain, calcium bound | Descriptor: | CALCIUM ION, Synaptotagmin-7 | Authors: | Tomchick, D.R, Rizo, J, Craig, T.K. | Deposit date: | 2010-05-24 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.441 Å) | Cite: | Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. Plos One, 5, 2010
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3OBV
| Autoinhibited Formin mDia1 Structure | Descriptor: | Protein diaphanous homolog 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | Authors: | Tomchick, D.R, Rosen, M.K, Otomo, T. | Deposit date: | 2010-08-09 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of the Formin mDia1 in autoinhibited conformation. Plos One, 5, 2010
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4NPK
| Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound | Descriptor: | CALCIUM ION, Extended synaptotagmin-2 | Authors: | Tomchick, D.R, Rizo, J, Xu, J. | Deposit date: | 2013-11-21 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.552 Å) | Cite: | Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2. Structure, 22, 2014
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4ONR
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4PKY
| ARNT/HIF transcription factor/coactivator complex | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, SULFATE ION, ... | Authors: | Tomchick, D.R, Partch, C.L, Gardner, K.H. | Deposit date: | 2014-05-15 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Coiled-coil Coactivators Play a Structural Role Mediating Interactions in Hypoxia-inducible Factor Heterodimerization. J.Biol.Chem., 290, 2015
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4NPJ
| Extended-Synaptotagmin 2, C2A- and C2B-domains | Descriptor: | ACETATE ION, CHLORIDE ION, Extended synaptotagmin-2, ... | Authors: | Tomchick, D.R, Rizo, J, Xu, J. | Deposit date: | 2013-11-21 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2. Structure, 22, 2014
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4R39
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5T8V
| Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment | Descriptor: | CITRIC ACID, Putative uncharacterized protein | Authors: | Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z. | Deposit date: | 2016-09-08 | Release date: | 2016-10-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy. Proc.Natl.Acad.Sci.USA, 113, 2016
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