2VYI
 
 | | Crystal Structure of the TPR domain of Human SGT | | Descriptor: | SGTA PROTEIN | | Authors: | Dutta, S, Tan, Y.J. | | Deposit date: | 2008-07-24 | | Release date: | 2008-08-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and Functional Characterization of Human Sgt and its Interaction with Vpu of the Human Immunodeficiency Virus Type 1.
Biochemistry, 47, 2008
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4A4D
 | | Crystal structure of the N-terminal domain of the Human DEAD-BOX RNA helicase DDX5 (P68) | | Descriptor: | PROBABLE ATP-DEPENDENT RNA HELICASE DDX5 | | Authors: | Dutta, S, Choi, Y.W, Kotaka, M, Fielding, B.C, Tan, Y.J. | | Deposit date: | 2011-10-11 | | Release date: | 2012-08-08 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Variable N-Terminal Region of Ddx5 Contains Structural Elements and Auto-Inhibits its Interaction with Ns5B of Hepatitis C Virus.
Biochem.J., 446, 2012
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4AQF
 | | X-ray crystallographic structure of Crimean-congo haemorrhagic fever virus nucleoprotein | | Descriptor: | NUCLEOPROTEIN, SULFATE ION | | Authors: | Wang, Y, Dutta, S, Karlberg, H, Devignot, S, Weber, F, Hao, Q, Tan, Y.J, Mirazimi, A, Kotaka, M. | | Deposit date: | 2012-04-17 | | Release date: | 2012-09-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of Crimean-Congo Haemorraghic Fever Virus Nucleoprotein: Superhelical Homo-Oligomers and the Role of Caspase-3 Cleavage.
J.Virol., 86, 2012
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4AQG
 | | X-ray crystallographic structure of Crimean-congo haemorrhagic fever virus nucleoprotein | | Descriptor: | NUCLEOPROTEIN, SULFATE ION | | Authors: | Wang, Y, Dutta, S, Karlberg, H, Devignot, S, Weber, F, Hao, Q, Tan, Y.J, Mirazimi, A, Kotaka, M. | | Deposit date: | 2012-04-17 | | Release date: | 2012-09-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of Crimean-Congo Haemorraghic Fever Virus Nucleoprotein: Superhelical Homo-Oligomers and the Role of Caspase-3 Cleavage.
J.Virol., 86, 2012
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2FA4
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5ZAD
 | | Human topoisomerase II beta in complex with DNA | | Descriptor: | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta | | Authors: | Sun, L.Y, Zhu, L.W, Tang, Y.J. | | Deposit date: | 2018-02-07 | | Release date: | 2019-03-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Increasing the distance between two monomers of topoisomerase II beta under the action of antitumor agent 4 beta-sulfur-(benzimidazole) 4'-demethylepipodophyllotoxin.
Sci Rep, 8, 2018
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5Y4B
 | | Solution structure of yeast Fra2 | | Descriptor: | BolA-like protein 2 | | Authors: | Tang, Y.J, Chi, C.B, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2017-08-03 | | Release date: | 2018-03-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3.
J. Mol. Biol., 430, 2018
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8VRG
 | | E. coli peptidyl-prolyl cis-trans isomerase containing delta1-monofluoro-leucines | | Descriptor: | Peptidyl-prolyl cis-trans isomerase B | | Authors: | Frkic, R.L, Jackson, C.J. | | Deposit date: | 2024-01-22 | | Release date: | 2024-05-22 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.22 Å) | | Cite: | Conformational Preferences of the Non-Canonical Amino Acids (2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.
Biochemistry, 63, 2024
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8VRH
 | | E. coli peptidyl-prolyl cis-trans isomerase containing delta2-monofluoro-leucines | | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Frkic, R.L, Jackson, C.J. | | Deposit date: | 2024-01-22 | | Release date: | 2024-05-22 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Conformational Preferences of the Non-Canonical Amino Acids (2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.
Biochemistry, 63, 2024
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8VRI
 | | E. coli peptidyl-prolyl cis-trans isomerase containing difluoro-leucines | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NONAETHYLENE GLYCOL, ... | | Authors: | Frkic, R.L, Jackson, C.J. | | Deposit date: | 2024-01-22 | | Release date: | 2024-05-22 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Conformational Preferences of the Non-Canonical Amino Acids (2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.
Biochemistry, 63, 2024
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3CTG
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7N3J
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8WN8
 | | CryoEM structure of ZIKV rsNS1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1 | | Authors: | Chew, B.L.A, Luo, D. | | Deposit date: | 2023-10-05 | | Release date: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
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8WO0
 | | CryoEM structure of ZIKV rsNS1 filament | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1 | | Authors: | Chew, B.L.A, Luo, D. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
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8WNP
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8WO4
 | | ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ... | | Authors: | Chew, B.L.A, Luo, D. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
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8WNU
 | | ZIKV rsNS1 in complex with Fab GB5 and anti-fab nanobody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ... | | Authors: | Chew, B.L.A, Luo, D. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
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7RFD
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7DNJ
 | | K63-polyUb MDA5CARDs complex | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, Ubiquitin | | Authors: | Song, B, Chen, Y, Luo, D.H, Zheng, J. | | Deposit date: | 2020-12-09 | | Release date: | 2021-10-13 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
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7DNI
 | | MDA5 CARDs-MAVS CARD polyUb complex | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin | | Authors: | Song, B, Chen, Y, Luo, D.H, Zheng, J. | | Deposit date: | 2020-12-09 | | Release date: | 2021-10-13 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
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8XUO
 | | Cryo-EM structure of tomato NRC2 dimer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2 | | Authors: | Sun, Y, Ma, S.C, Chai, J.J. | | Deposit date: | 2024-01-13 | | Release date: | 2024-05-22 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR.
Nature, 2024
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8XUV
 | | Cryo-EM structure of tomato NRC2 filament | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2 | | Authors: | Sun, Y, Ma, S.C, Chai, J.J. | | Deposit date: | 2024-01-14 | | Release date: | 2024-05-22 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR.
Nature, 2024
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8XUQ
 | | Cryo-EM structure of tomato NRC2 tetramer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2 | | Authors: | Sun, Y, Ma, S.C, Chai, J.J. | | Deposit date: | 2024-01-14 | | Release date: | 2024-05-22 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR.
Nature, 2024
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5JCB
 | | Microtubule depolymerizing agent podophyllotoxin derivative YJTSF1 | | Descriptor: | (5R,5aR,8aS,9R)-9-[(4H-1,2,4-triazol-3-yl)sulfanyl]-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Guan, Z, Zhao, W, Yin, P. | | Deposit date: | 2016-04-14 | | Release date: | 2017-09-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Insights into the Inhibition of Tubulin by the Antitumor Agent 4 beta-(1,2,4-triazol-3-ylthio)-4-deoxypodophyllotoxin.
ACS Chem. Biol., 12, 2017
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5Y4S
 | | Structure of a methyltransferase complex | | Descriptor: | Chemotaxis protein methyltransferase 1 | | Authors: | Yan, X, Xin, L, Tan, Y.J, Jin, S, Liang, Z.X, Gao, Y.G. | | Deposit date: | 2017-08-04 | | Release date: | 2017-11-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.405 Å) | | Cite: | Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein.
J. Biol. Chem., 293, 2018
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