8VRI

E. coli peptidyl-prolyl cis-trans isomerase containing difluoro-leucines

Summary for 8VRI

• Entry DOI: 10.2210/pdb8vri/pdb
• Descriptor: Peptidyl-prolyl cis-trans isomerase B, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ... (8 entities in total)
• Functional Keywords: peptidyl-prolyl cis-trans isomerase, non-canonical amino acids, fluorinated leucine, isomerase
• Biological source: Escherichia coli; More
• Total number of polymer chains: 5
• Total formula weight: 98040.58

Authors

Frkic, R.L.,Jackson, C.J. (deposition date: 2024-01-22, release date: 2024-05-22, Last modification date: 2024-05-29)

• Primary citation: Frkic, R.L.,Tan, Y.J.,Abdelkader, E.H.,Maleckis, A.,Tarcoveanu, E.,Nitsche, C.,Otting, G.,Jackson, C.J.; Conformational Preferences of the Non-Canonical Amino Acids (2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.; Biochemistry, 2024; PubMed: 38742763; DOI: 10.1021/acs.biochem.4c00081

Experimental method

X-RAY DIFFRACTION (1.65 Å)