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6ULN
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BU of 6uln by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Descriptor: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, GLYCEROL, ...
Authors:Sun, P.D, Sim, M.J.W.
Deposit date:2019-10-08
Release date:2020-05-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UON
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BU of 6uon by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Descriptor: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA-LEU, HLA class I antigen, ...
Authors:Sun, P.D, Sim, M.J.W.
Deposit date:2019-10-15
Release date:2020-05-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
1FDO
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BU of 1fdo by Molmil
OXIDIZED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI
Descriptor: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FORMATE DEHYDROGENASE H, IRON/SULFUR CLUSTER, ...
Authors:Sun, P.D, Boyington, J.C.
Deposit date:1997-01-27
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.
Science, 275, 1997
1FDI
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BU of 1fdi by Molmil
OXIDIZED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI COMPLEXED WITH THE INHIBITOR NITRITE
Descriptor: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FORMATE DEHYDROGENASE H, IRON/SULFUR CLUSTER, ...
Authors:Sun, P.D, Boyington, J.C.
Deposit date:1997-01-28
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.
Science, 275, 1997
1AA6
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BU of 1aa6 by Molmil
REDUCED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI
Descriptor: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FORMATE DEHYDROGENASE H, IRON/SULFUR CLUSTER, ...
Authors:Sun, P.D, Boyington, J.C.
Deposit date:1997-01-23
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.
Science, 275, 1997
6ULR
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BU of 6ulr by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Descriptor: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, HLA class I antigen, ...
Authors:Sun, P.D, Sim, M.J.W.
Deposit date:2019-10-08
Release date:2020-05-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ULI
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BU of 6uli by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Descriptor: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, HLA class I antigen
Authors:Sun, P.D, Sim, M.J.W.
Deposit date:2019-10-08
Release date:2020-05-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ULK
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BU of 6ulk by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
Descriptor: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA-LEU, HLA class I antigen
Authors:Sun, P.D, Sim, M.J.W.
Deposit date:2019-10-08
Release date:2020-05-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
2DLI
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BU of 2dli by Molmil
KILLER IMMUNOGLOBULIN RECEPTOR 2DL2,TRIGONAL FORM
Descriptor: PROTEIN (MHC CLASS I NK CELL RECEPTOR PRECURSOR)
Authors:Sun, P.D, Snyder, G.A.
Deposit date:1999-03-08
Release date:2000-01-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2
Proc.Natl.Acad.Sci.USA, 96, 1999
3KHQ
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BU of 3khq by Molmil
Crystal structure of murine Ig-beta (CD79b) in the monomeric form
Descriptor: B-cell antigen receptor complex-associated protein beta chain, CITRATE ANION, GLUTATHIONE, ...
Authors:Radaev, S, Sun, P.D.
Deposit date:2009-10-30
Release date:2010-08-25
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
1EFX
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BU of 1efx by Molmil
STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3
Descriptor: BETA-2-MICROGLOBULIN, HLA-CW3 (HEAVY CHAIN), NATURAL KILLER CELL RECEPTOR KIR2DL2, ...
Authors:Boyington, J.C, Motyka, S.A, Schuck, P, Brooks, A.G, Sun, P.D.
Deposit date:2000-02-10
Release date:2000-06-14
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.
Nature, 405, 2000
4X4M
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BU of 4x4m by Molmil
Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high affinity IgG binding
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2014-12-03
Release date:2015-04-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.485 Å)
Cite:Structure of Fc gamma RI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding.
Proc.Natl.Acad.Sci.USA, 112, 2015
3RJD
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BU of 3rjd by Molmil
Crystal structure of Fc RI and its implication to high affinity immunoglobulin G binding
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2011-04-15
Release date:2011-09-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of Fc gamma receptor I and its implication in high affinity gamma-immunoglobulin binding.
J.Biol.Chem., 286, 2011
1FNL
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BU of 1fnl by Molmil
CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF A HUMAN FCGRIII
Descriptor: LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III-B, MERCURY (II) ION
Authors:Zhang, Y, Boesen, C.C, Radaev, S, Brooks, A.G, Fridman, W.H, Sautes-Fridman, C, Sun, P.D.
Deposit date:2000-08-22
Release date:2000-11-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the extracellular domain of a human Fc gamma RIII.
Immunity, 13, 2000
2ZG3
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BU of 2zg3 by Molmil
Crystal Structure of Two N-terminal Domains of Native Siglec-5 in Complex with 3'-Sialyllactose
Descriptor: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Sialic acid-binding Ig-like lectin 5
Authors:Zhuravleva, M.A, Sun, P.D.
Deposit date:2008-01-17
Release date:2008-02-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
7SU9
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BU of 7su9 by Molmil
KRAS-G12D specific TCR9a in complex with C*05-GADGVGKSL
Descriptor: Beta-2-microglobulin, GLYCEROL, KRAS-G12D-9mer with A18L substitution, ...
Authors:Sim, M.J.W, Sun, P.D.
Deposit date:2021-11-16
Release date:2022-06-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:T cells discriminate between groups C1 and C2 HLA-C.
Elife, 11, 2022
2ZG1
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BU of 2zg1 by Molmil
Crystal Structure of Two N-terminal Domains of Siglec-5 in Complex with 6'-Sialyllactose
Descriptor: N-acetyl-alpha-neuraminic acid, Sialic acid-binding Ig-like lectin 5
Authors:Zhuravleva, M.A, Sun, P.D.
Deposit date:2008-01-17
Release date:2008-02-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
2ZG2
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BU of 2zg2 by Molmil
Crystal Structure of Two N-terminal Domains of Native Siglec-5
Descriptor: Sialic acid-binding Ig-like lectin 5
Authors:Zhuravleva, M.A, Sun, P.D.
Deposit date:2008-01-17
Release date:2008-02-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural implications of Siglec-5-mediated sialoglycan recognition
J.Mol.Biol., 375, 2008
8VJZ
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BU of 8vjz by Molmil
HLA-A*03:01 with WT KRAS-10mer
Descriptor: Beta-2-microglobulin, GLYCEROL, GTPase KRas, ...
Authors:Sim, M.J.W, Sun, P.D.
Deposit date:2024-01-08
Release date:2024-12-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification and structural characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3.
Eur.J.Immunol., 54, 2024
1B6E
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BU of 1b6e by Molmil
HUMAN CD94
Descriptor: CD94
Authors:Boyington, J.C, Riaz, A.N, Patamawenu, A, Coligan, J.E, Brooks, A.G, Sun, P.D.
Deposit date:1999-01-14
Release date:1999-06-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors.
Immunity, 10, 1999
3D5O
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BU of 3d5o by Molmil
Structural recognition and functional activation of FcrR by innate pentraxins
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Low affinity immunoglobulin gamma Fc region receptor II-a, ...
Authors:Lu, J, Marnell, L.L, Marjon, K.D, Mold, C, Du Clos, T.W, Sun, P.D.
Deposit date:2008-05-16
Release date:2008-11-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural recognition and functional activation of FcgammaR by innate pentraxins.
Nature, 456, 2008
3KG5
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BU of 3kg5 by Molmil
Crystal structure of human Ig-beta homodimer
Descriptor: B-cell antigen receptor complex-associated protein beta chain
Authors:Radaev, S, Sun, P.D.
Deposit date:2009-10-28
Release date:2010-08-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
3KHO
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BU of 3kho by Molmil
Crystal structure of murine Ig-beta (CD79b) homodimer
Descriptor: B-cell antigen receptor complex-associated protein beta chain, SULFATE ION
Authors:Radaev, S, Sun, P.D.
Deposit date:2009-10-30
Release date:2010-08-25
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
8RRO
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BU of 8rro by Molmil
G12V-TCR complex with HLA-A3
Descriptor: Beta-2-microglobulin, G12V-TCR alpha chain, G12V-TCR beta chain, ...
Authors:Sim, M.J.W, Sun, P.D.
Deposit date:2024-01-23
Release date:2024-11-20
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Identification and structural characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3.
Eur.J.Immunol., 54, 2024
6C68
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BU of 6c68 by Molmil
MHC-independent t cell receptor A11
Descriptor: T-cell receptor alpha chain, T-cell receptor beta chain
Authors:Lu, J, Van Laethem, F, Saba, I, Chu, J, Bhattacharya, A, Love, N.C, Tikhonova, A, Radaev, S, Sun, X, Ko, A, Arnon, T, Shifrut, E, Friedman, N, Weng, N, Singer, A, Sun, P.D.
Deposit date:2018-01-18
Release date:2019-01-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure of MHC-Independent TCRs and Their Recognition of Native Antigen CD155.
J Immunol., 204, 2020

 

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