5T5S
| A fragment of a human tRNA synthetase | Descriptor: | Alanine--tRNA ligase, cytoplasmic | Authors: | Sun, L, Schimmel, P. | Deposit date: | 2016-08-31 | Release date: | 2016-11-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5T76
| A fragment of a human tRNA synthetase | Descriptor: | Alanine--tRNA ligase, cytoplasmic | Authors: | Sun, L, Schimmel, P. | Deposit date: | 2016-09-02 | Release date: | 2016-11-30 | Last modified: | 2017-01-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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7WHK
| The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2021-12-30 | Release date: | 2022-05-11 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
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7WHI
| The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2021-12-30 | Release date: | 2022-05-11 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
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7WHJ
| The state 1 complex structure of Omicron spike with Bn03 (1-up RBD, 3 nanobodies) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | Authors: | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2021-12-30 | Release date: | 2022-05-11 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
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7CO3
| HtrA-type protease AlgWS227A with tripeptide | Descriptor: | AlgW protein, TRP-VAL-PHE | Authors: | Li, T, Song, Y.J, Bao, R. | Deposit date: | 2020-08-03 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa. Mbio, 12, 2021
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7CO5
| HtrA-type protease AlgW with decapeptide | Descriptor: | AlgW protein, IMIDAZOLE, decapeptide SVRDELRWVF | Authors: | Li, T, Song, Y.J, Bao, R. | Deposit date: | 2020-08-03 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.345 Å) | Cite: | Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa. Mbio, 12, 2021
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7CO2
| HtrA-type protease AlgW with tripeptide | Descriptor: | AlgW protein, IMIDAZOLE, TRP-VAL-PHE | Authors: | Li, T, Song, Y.J, Bao, R. | Deposit date: | 2020-08-03 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa. Mbio, 12, 2021
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7CO7
| HtrA-type protease AlgWS227A with decapeptide | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, AlgW protein, decapeptide SVRDELRWVF | Authors: | Li, T, Song, Y.J, Bao, R. | Deposit date: | 2020-08-04 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa. Mbio, 12, 2021
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7VK9
| Crystal structure of xCas9 P411T | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1 | Authors: | Bao, R, Liu, H.Y, Luo, Y.Z, Song, Y.J. | Deposit date: | 2021-09-29 | Release date: | 2022-04-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and Dynamics Studies of the Spcas9 Variant Provide Insights into the Regulatory Role of the REC1 Domain Acs Catalysis, 12, 2022
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2ZCS
| Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-700 | Descriptor: | Dehydrosqualene synthase, tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. | Deposit date: | 2007-11-11 | Release date: | 2008-03-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008
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2ZCQ
| Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-652 | Descriptor: | (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid, Dehydrosqualene synthase, MAGNESIUM ION | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. | Deposit date: | 2007-11-11 | Release date: | 2008-03-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008
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8HT7
| The N-terminal region of Cdc6 specifically recognizes human DNA G-quadruplex | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*TP*GP*GP*G)-3'), GLN-ALA-GLN-ALA-THR-ILE-SER-PHE-PRO-LYS-ARG-LYS-LEU-SER-TRP | Authors: | Liu, C, Zhu, G, Geng, Y, Xu, N. | Deposit date: | 2022-12-20 | Release date: | 2023-12-27 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The N-terminal region of Cdc6 specifically recognizes human DNA G-quadruplex. Int.J.Biol.Macromol., 260, 2024
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2ZCO
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2ZCR
| Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-698 | Descriptor: | Dehydrosqualene synthase, MAGNESIUM ION, tripotassium (1R)-4-(4'-butylbiphenyl-4-yl)-1-phosphonatobutane-1-sulfonate | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. | Deposit date: | 2007-11-11 | Release date: | 2008-03-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008
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3BGL
| Hepatoselectivity of Statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors | Descriptor: | (3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-4-(morpholin-4-ylsulfonyl)-3-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Authors: | Finzel, B.C, Pavlovsky, A, Park, W.K.C. | Deposit date: | 2007-11-26 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.225 Å) | Cite: | Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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6LA5
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6LB1
| Cryo-EM structure of echovirus 11 A-particle at pH 5.5 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Liu, S, Gao, F.G. | Deposit date: | 2019-11-13 | Release date: | 2020-10-07 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn. Chin.Sci.Bull., 2020
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6LA7
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6LA3
| Cryo-EM structure of full echovirus 11 particle at pH 7.4 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Liu, S, Gao, F.G. | Deposit date: | 2019-11-11 | Release date: | 2020-10-07 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn. Chin.Sci.Bull., 2020
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6LAO
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6LBO
| Cryo-EM structure of echovirus 11 empty particle at pH 7.4 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Liu, S, Gao, F.G. | Deposit date: | 2019-11-14 | Release date: | 2020-10-07 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn. Chin.Sci.Bull., 2020
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6LBQ
| Cryo-EM structure of echovirus 11 empty particle at pH 5.5 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Liu, S, Gao, F.G. | Deposit date: | 2019-11-14 | Release date: | 2020-10-07 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn. Chin.Sci.Bull., 2020
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6LA4
| Cryo-EM structure of full echovirus 11 particle at pH 5.5 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Liu, S, Gao, F.G. | Deposit date: | 2019-11-11 | Release date: | 2020-10-07 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn. Chin.Sci.Bull., 2020
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6LAP
| Cryo-EM structure of echovirus 11 A-particle at pH 7.4 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Liu, S, Gao, F.G. | Deposit date: | 2019-11-13 | Release date: | 2020-10-07 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn. Chin.Sci.Bull., 2020
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