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8GIO
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BU of 8gio by Molmil
Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.1mM Mn2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-03-14
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.1mM Mn2+
To Be Published
8GIT
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BU of 8git by Molmil
Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 1mM Mn2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-03-14
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 1mM Mn2+
To Be Published
1YM9
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BU of 1ym9 by Molmil
Crystal structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfinic form
Descriptor: CHLORIDE ION, M-phase inducer phosphatase 2
Authors:Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C.
Deposit date:2005-01-20
Release date:2005-04-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond
Biochemistry, 44, 2005
1YML
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BU of 1yml by Molmil
Crystal Structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfenic form
Descriptor: CHLORIDE ION, M-phase inducer phosphatase 2
Authors:Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C.
Deposit date:2005-01-21
Release date:2005-04-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond
Biochemistry, 44, 2005
1YMD
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BU of 1ymd by Molmil
Crystal Structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfonic form
Descriptor: CHLORIDE ION, M-phase inducer phosphatase 2
Authors:Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C.
Deposit date:2005-01-20
Release date:2005-04-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond
Biochemistry, 44, 2005
1YS0
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BU of 1ys0 by Molmil
Crystal Structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the disulfide form
Descriptor: CHLORIDE ION, M-phase inducer phosphatase 2
Authors:Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C.
Deposit date:2005-02-05
Release date:2005-04-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond
Biochemistry, 44, 2005
1YMK
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BU of 1ymk by Molmil
Crystal Structure of the CDC25B phosphatase catalytic domain in the apo form
Descriptor: CHLORIDE ION, M-phase inducer phosphatase 2
Authors:Buhrman, G.K, Parker, B, Sohn, J, Rudolph, J, Mattos, C.
Deposit date:2005-01-21
Release date:2005-04-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond
Biochemistry, 44, 2005
8SHK
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BU of 8shk by Molmil
Structure of binary complex of mouse cGAS and bound ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ZINC ION
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-14
Release date:2024-04-24
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure of binary complex of mouse cGAS and bound ATP
To Be Published
8SHU
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BU of 8shu by Molmil
Structure of mouse cGAS
Descriptor: Cyclic GMP-AMP synthase, ZINC ION
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-14
Release date:2024-04-24
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure of mouse cGAS
To Be Published
8SHZ
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BU of 8shz by Molmil
Structure of human cGAS
Descriptor: Cyclic GMP-AMP synthase, ZINC ION
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-14
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of human cGAS
To Be Published
8SJ1
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BU of 8sj1 by Molmil
Structure of ternary complex of cGAS with dsDNA and bound 3'-dATP
Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-17
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structure of ternary complex of cGAS with dsDNA and bound 3'-dATP
To Be Published
8SJ0
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BU of 8sj0 by Molmil
Structure of ternary complex of cGAS with dsDNA and bound 2'-dATP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-17
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of ternary complex of cGAS with dsDNA and bound 2'-dATP
To Be Published
8SKT
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BU of 8skt by Molmil
Structure of ternary complex of mouse cGAS with dsDNA and bound ATP with 5 mM Mn2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-20
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structure of ternary complex of mouse cGAS with dsDNA and bound ATP with 5 mM Mn2+
To Be Published
8SI0
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BU of 8si0 by Molmil
Structure of binary complex of human cGAS and bound cGAMP
Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cGAMP
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-14
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of binary complex of human cGAS and bound cGAMP
To Be Published
8SHY
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BU of 8shy by Molmil
Structure of binary complex of mouse cGAS QN and bound ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ZINC ION
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-14
Release date:2024-04-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure of binary complex of mouse cGAS QN and bound ATP
To Be Published
8SJ2
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BU of 8sj2 by Molmil
Structure of ternary complex of cGAS with dsDNA and bound ATP and 2'-dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-17
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of ternary complex of cGAS with dsDNA and bound ATP and 2'-dGTP
To Be Published
8SJ8
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BU of 8sj8 by Molmil
Structure of binary complex of human cGAS and bound ppp(2'-5')GpG
Descriptor: Cyclic GMP-AMP synthase, ZINC ION, [[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-17
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of binary complex of human cGAS and bound ppp(2'-5')GpG
to be published
2IFV
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BU of 2ifv by Molmil
Crystal structure of an active site mutant, C473D, of CDC25B phosphatase catalytic domain
Descriptor: CHLORIDE ION, M-phase inducer phosphatase 2
Authors:Rudolph, J, Buhrman, G.
Deposit date:2006-09-21
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Kinetic and structural studies of specific protein-protein interactions in substrate catalysis by Cdc25B phosphatase.
Biochemistry, 46, 2007
2IFD
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BU of 2ifd by Molmil
Crystal structure of a remote binding site mutant, R492L, of CDC25B Phosphatase catalytic domain
Descriptor: CHLORIDE ION, M-phase inducer phosphatase 2, SULFATE ION
Authors:Rudolph, J, Buhrman, G.
Deposit date:2006-09-20
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural studies of specific protein-protein interactions in substrate catalysis by Cdc25B phosphatase.
Biochemistry, 46, 2007
7UTT
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BU of 7utt by Molmil
Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination
Descriptor: Cyclic GMP-AMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION, ...
Authors:Wu, S, Gabelli, S.B, Sohn, J.
Deposit date:2022-04-27
Release date:2023-05-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination
To Be Published
7UUX
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BU of 7uux by Molmil
ATP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ...
Authors:Wu, S, Gabelli, S.B, Sohn, J.
Deposit date:2022-04-29
Release date:2023-05-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:ATP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination
To Be Published
7V0W
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BU of 7v0w by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2,5 )pA
Descriptor: ADENOSINE-5'-MONOPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Wu, S, Gabelli, S.B, Sohn, J.
Deposit date:2022-05-11
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pA
To Be Published
7UXW
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BU of 7uxw by Molmil
Structure of ATP and GTP bind to Cyclic GMP AMP synthase (cGAS) through Mg coordination
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Wu, S, Gabelli, S.B, Sohn, J.
Deposit date:2022-05-06
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:ATP and GTP bind to Cyclic GMP AMP synthase (cGAS) through Mg coordination
To Be Published
7UYQ
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BU of 7uyq by Molmil
Structure of GTP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination
Descriptor: Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Wu, S, Gabelli, S.B, Sohn, J.
Deposit date:2022-05-07
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structure of GTP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination
To Be Published
7UYZ
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BU of 7uyz by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG
Descriptor: Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Wu, S, Gabelli, S.B, Sohn, J.
Deposit date:2022-05-07
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG
To Be Published

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