2IFV

Crystal structure of an active site mutant, C473D, of CDC25B phosphatase catalytic domain

Summary for 2IFV

Entry DOI	10.2210/pdb2ifv/pdb
Related	1QB0 1YMK 2A2K 2IFD
Descriptor	M-phase inducer phosphatase 2, CHLORIDE ION (3 entities in total)
Functional Keywords	phosphatase, dual specificity, active site mutant, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton, centrosome: P30305
Total number of polymer chains	1
Total formula weight	20764.65
Authors	Rudolph, J.,Buhrman, G. (deposition date: 2006-09-21, release date: 2007-02-27, Last modification date: 2023-08-30)
Primary citation	Sohn, J.,Buhrman, G.,Rudolph, J. Kinetic and structural studies of specific protein-protein interactions in substrate catalysis by Cdc25B phosphatase. Biochemistry, 46:807-818, 2007 Cited by PubMed: 17223702 DOI: 10.1021/bi061257y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation