2IFV
Crystal structure of an active site mutant, C473D, of CDC25B phosphatase catalytic domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | M-phase inducer phosphatase 2 | polymer | 175 | 20693.7 | 1 | UniProt (P30305) Pfam (PF00581) In PDB | Homo sapiens (human) | Dual specificity phosphatase Cdc25B |
| 2 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A: 377 - 550 (UniProt: P30305)
| PDB | External Database | Details |
|---|---|---|
| Met 376 | - | initiating methionine |
| Asp 473 | Cys 487 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20693.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 20764.7 |
