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3LGT
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BU of 3lgt by Molmil
Y162A/H198P double mutant of DegS-deltaPDZ protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LH3
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BU of 3lh3 by Molmil
DFP modified DegS delta PDZ
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGI
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BU of 3lgi by Molmil
Structure of the protease domain of DegS (DegS-deltaPDZ) at 1.65 A
Descriptor: PHOSPHATE ION, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-20
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.652 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LH1
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BU of 3lh1 by Molmil
Q191A mutant of the DegS-deltaPDZ
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.507 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGU
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BU of 3lgu by Molmil
Y162A mutant of the DegS-deltaPDZ protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGV
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BU of 3lgv by Molmil
H198P mutant of the DegS-deltaPDZ protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.734 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGW
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BU of 3lgw by Molmil
H198P/T167V double mutant of DegS-deltaPDZ protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3LGY
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BU of 3lgy by Molmil
R178A mutant of the DegS-deltaPDZ protease
Descriptor: CHLORIDE ION, MAGNESIUM ION, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2010-01-21
Release date:2010-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
3GCO
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BU of 3gco by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYQF OMP peptide
Descriptor: DNRDGNVYQF peptide, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-22
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GCN
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BU of 3gcn by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with OMP peptide (YQF)
Descriptor: Protease degS, YQF peptide
Authors:Sohn, J, Sauer, R.T, Grant, R.A.
Deposit date:2009-02-22
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Mechanisms of allosteric activation of the DegS protease by OMP-peptide binding and protein-substrate binding
To be Published
2A2K
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BU of 2a2k by Molmil
Crystal Structure of an active site mutant, C473S, of Cdc25B Phosphatase Catalytic Domain
Descriptor: CHLORIDE ION, M-phase inducer phosphatase 2, SULFATE ION
Authors:Sohn, J, Parks, J, Buhrman, G, Brown, P, Kristjansdottir, K, Safi, A, Yang, W, Edelsbrunner, H, Rudolph, J.
Deposit date:2005-06-22
Release date:2006-01-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Experimental Validation of the Docking Orientation of Cdc25 with Its Cdk2-CycA Protein Substrate.
Biochemistry, 44, 2005
3GDS
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BU of 3gds by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYYF peptide
Descriptor: DNRDGNVYYF peptide, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GDU
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BU of 3gdu by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YRF peptide
Descriptor: DegS protease, YRF peptide
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
3GDV
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BU of 3gdv by Molmil
Crystal structure of DegS H198P/D320A mutant modified by DFP and in complex with YQF peptide
Descriptor: DegS protease, YQF peptide
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2009-02-24
Release date:2009-03-31
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.489 Å)
Cite:OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism.
Structure, 17, 2009
2QGR
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BU of 2qgr by Molmil
Structure of the R178A mutant of delta PDZ DegS protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2007-06-29
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Allosteric activation of DegS, a stress sensor PDZ protease.
Cell(Cambridge,Mass.), 131, 2007
2RCE
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BU of 2rce by Molmil
DFP modified DegS delta PDZ
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2007-09-19
Release date:2007-12-11
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:DFP modified DegS delta PDZ
To be Published
2QF3
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BU of 2qf3 by Molmil
Structure of the delta PDZ truncation of the DegS protease
Descriptor: PHOSPHATE ION, Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2007-06-26
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Allosteric activation of DegS, a stress sensor PDZ protease.
Cell(Cambridge,Mass.), 131, 2007
2QF0
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BU of 2qf0 by Molmil
Structure of the delta PDZ truncation of the DegS protease
Descriptor: Protease degS
Authors:Sohn, J, Grant, R.A, Sauer, R.T.
Deposit date:2007-06-26
Release date:2007-12-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric activation of DegS, a stress sensor PDZ protease.
Cell(Cambridge,Mass.), 131, 2007
3B8J
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BU of 3b8j by Molmil
Q191A mutant of DegS-deltaPDZ
Descriptor: Protease degS
Authors:Grant, R.A, Sohn, J, Sauer, R.T.
Deposit date:2007-11-01
Release date:2008-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.507 Å)
Cite:biochemical characterization of DegS-deltaPDZ q191A mutant
To be Published
6MKS
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BU of 6mks by Molmil
Cryo-EM structure of NLRC4-CARD filament
Descriptor: Chimera protein of NLR family CARD domain-containing protein 4 and EGFP
Authors:Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
Deposit date:2018-09-26
Release date:2018-11-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J. Biol. Chem., 293, 2018
7K3R
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BU of 7k3r by Molmil
Cryo-EM structure of AIM2-PYD filament
Descriptor: Interferon-inducible protein AIM2
Authors:Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
Deposit date:2020-09-12
Release date:2021-05-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome.
Nat Commun, 12, 2021
8EAE
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BU of 8eae by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppG(2,5)pI
Descriptor: Cyclic GMP-AMP synthase, MAGNESIUM ION, Palindromic DNA18, ...
Authors:Wu, S, Sohn, J.
Deposit date:2022-08-29
Release date:2023-10-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
8ECC
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BU of 8ecc by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppI(2,5)pA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2022-09-01
Release date:2024-01-17
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppI(2,5)pA
To Be Published
8G1J
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BU of 8g1j by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and ITP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-02-02
Release date:2024-05-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
8G10
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BU of 8g10 by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound ITP and GTP
Descriptor: Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-02-01
Release date:2024-05-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024

 

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