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8ECC

Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppI(2,5)pA

Summary for 8ECC
Entry DOI10.2210/pdb8ecc/pdb
DescriptorCyclic GMP-AMP synthase, Palindromic DNA18, ADENOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
Functional Keywordstransferase-dna complex, cgas, 5-pppi(2, 5)pa, immune system, transferase, transferase/dna
Biological sourceMus musculus (house mouse)
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Total number of polymer chains6
Total formula weight108862.90
Authors
Wu, S.,Sohn, J. (deposition date: 2022-09-01, release date: 2024-01-17)
Primary citationWu, S.,Sohn, J.
Structure of Ternary Complex of cGAS with dsDNA and Bound 5-pppI(2,5)pA
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.44 Å)
Structure validation

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