1XXS
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![BU of 1xxs by Molmil](/molmil-images/mine/1xxs) | Structural insights for fatty acid binding in a Lys49 phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid | Descriptor: | Phospholipase A2 homolog 2, STEARIC ACID, SULFATE ION | Authors: | Watanabe, L, Soares, A.M, Ward, R.J, Fontes, M.R, Arni, R.K. | Deposit date: | 2004-11-08 | Release date: | 2005-03-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights for fatty acid binding in a Lys49-phospholipase A(2): crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid Biochimie, 87, 2005
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1Z76
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![BU of 1z76 by Molmil](/molmil-images/mine/1z76) | Crystal structure of an acidic phospholipase A2 (BthA-I) from Bothrops jararacussu venom complexed with p-bromophenacyl bromide | Descriptor: | p-Bromophenacyl bromide, phospholipase A2 | Authors: | Magro, A.J, Takeda, A.A, Soares, A.M, Fontes, M.R. | Deposit date: | 2005-03-24 | Release date: | 2006-03-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of BthA-I complexed with p-bromophenacyl bromide: possible correlations with lack of pharmacological activity. Acta Crystallogr.,Sect.D, 61, 2005
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1PA0
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![BU of 1pa0 by Molmil](/molmil-images/mine/1pa0) | CRYSTAL STRUCTURE OF BNSP-7, A LYS49-PHOSPHOLIPASE A2 | Descriptor: | Myotoxic phospholipase A2-like | Authors: | Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R. | Deposit date: | 2003-05-13 | Release date: | 2004-07-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights. Biochem.Biophys.Res.Commun., 311, 2003
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1PC9
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![BU of 1pc9 by Molmil](/molmil-images/mine/1pc9) | Crystal Structure of BnSP-6, a Lys49-Phospholipase A2 | Descriptor: | BnSP-6 | Authors: | Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.M. | Deposit date: | 2003-05-16 | Release date: | 2004-06-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights. Biochem.Biophys.Res.Commun., 311, 2003
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1U73
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![BU of 1u73 by Molmil](/molmil-images/mine/1u73) | Crystal structure of a Dimeric Acidic Platelet Aggregation Inhibitor and Hypotensive Phospholipase A2 from Bothrops jararacussu | Descriptor: | hypotensive phospholipase A2 | Authors: | Magro, A.J, Murakami, M.T, Soares, A.M, Arni, R.K, Fontes, M.R. | Deposit date: | 2004-08-02 | Release date: | 2004-10-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A(2) in the monomeric and dimeric states: insights into its oligomeric state Biochem.Biophys.Res.Commun., 323, 2004
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3IQ3
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![BU of 3iq3 by Molmil](/molmil-images/mine/3iq3) | Crystal Structure of Bothropstoxin-I complexed with polietilene glicol 4000 - crystallized at 283 K | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Phospholipase A2 homolog bothropstoxin-1, SULFATE ION | Authors: | Salvador, G.H.M, Marchi-Salvador, D.P, Silva, M.C.O, Soares, A.M, Fontes, M.R.M. | Deposit date: | 2009-08-19 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s. J.Struct.Biol., 171, 2010
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3HZD
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![BU of 3hzd by Molmil](/molmil-images/mine/3hzd) | Crystal structure of bothropstoxin-I (BthTX-I), a PLA2 homologue from Bothrops jararacussu venom | Descriptor: | LITHIUM ION, Phospholipase A2 homolog bothropstoxin-1 | Authors: | Silva, M.C.O, Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M. | Deposit date: | 2009-06-23 | Release date: | 2009-07-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s. J.Struct.Biol., 171, 2010
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3I3H
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![BU of 3i3h by Molmil](/molmil-images/mine/3i3h) | |
3HZW
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![BU of 3hzw by Molmil](/molmil-images/mine/3hzw) | Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) | Descriptor: | ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide | Authors: | Fernandes, C.A.H, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M. | Deposit date: | 2009-06-24 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s. J.Struct.Biol., 171, 2010
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3I3I
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![BU of 3i3i by Molmil](/molmil-images/mine/3i3i) | |
3I03
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![BU of 3i03 by Molmil](/molmil-images/mine/3i03) | Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) - monomeric form at a high resolution | Descriptor: | ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide | Authors: | Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M. | Deposit date: | 2009-06-24 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s. J.Struct.Biol., 171, 2010
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2OQD
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![BU of 2oqd by Molmil](/molmil-images/mine/2oqd) | Crystal Structure of BthTX-II | Descriptor: | Phospholipase A2 | Authors: | Correa, L.C, Marchi-Salvador, D.P, Cintra, A.C.O, Soares, A.M, Fontes, M.R.M. | Deposit date: | 2007-01-31 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal structure of a myotoxic Asp49-phospholipase A(2) with low catalytic activity: Insights into Ca(2+)-independent catalytic mechanism. Biochim.Biophys.Acta, 1784, 2008
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2OK9
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![BU of 2ok9 by Molmil](/molmil-images/mine/2ok9) | PrTX-I-BPB | Descriptor: | ISOPROPYL ALCOHOL, Phospholipase A2 homolog 1, p-Bromophenacyl bromide | Authors: | Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R. | Deposit date: | 2007-01-16 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Crystal structure of a phospholipase A(2) homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity. Biochim.Biophys.Acta, 1794, 2009
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8DND
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![BU of 8dnd by Molmil](/molmil-images/mine/8dnd) | |
4YU7
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![BU of 4yu7 by Molmil](/molmil-images/mine/4yu7) | Crystal structure of Piratoxin I (PrTX-I) complexed to caffeic acid | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog piratoxin-1, CAFFEIC ACID, ... | Authors: | Fernandes, C.A.H, Fontes, M.R.M. | Deposit date: | 2015-03-18 | Release date: | 2015-08-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.647 Å) | Cite: | Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids. Plos One, 10, 2015
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4YZ7
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![BU of 4yz7 by Molmil](/molmil-images/mine/4yz7) | Crystal structure of Piratoxin I (PrTX-I) complexed to aristolochic acid | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 9-HYDROXY ARISTOLOCHIC ACID, Basic phospholipase A2 homolog piratoxin-1, ... | Authors: | Fernandes, C.A.H, Fontes, M.R.M. | Deposit date: | 2015-03-24 | Release date: | 2015-08-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9589 Å) | Cite: | Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids. Plos One, 10, 2015
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7ROX
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![BU of 7rox by Molmil](/molmil-images/mine/7rox) | BthTX-I complexed with inhibitor MMV | Descriptor: | 12-methoxy-Nb-methylvoachalotine, Basic phospholipase A2 homolog bothropstoxin-I | Authors: | Borges, R.J, De Marino, I, Uson, I, Fontes, M.R.M. | Deposit date: | 2021-08-02 | Release date: | 2022-11-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional studies of a snake venom phospholipase A 2 -like protein complexed to an inhibitor from Tabernaemontana catharinensis. Biochimie, 206, 2023
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3QNL
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![BU of 3qnl by Molmil](/molmil-images/mine/3qnl) | Crystal structure of PrTX-I complexed to Rosmarinic Acid | Descriptor: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ISOPROPYL ALCOHOL, ... | Authors: | dos Santos, J.I, Fontes, M.R.M. | Deposit date: | 2011-02-08 | Release date: | 2012-02-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition. Plos One, 6, 2011
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3CYL
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![BU of 3cyl by Molmil](/molmil-images/mine/3cyl) | |
3CXI
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![BU of 3cxi by Molmil](/molmil-images/mine/3cxi) | Structure of BthTX-I complexed with alpha-tocopherol | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Myotoxic phospholipase A2-like, SULFATE ION, ... | Authors: | dos Santos, J.I, Fontes, M.R.M. | Deposit date: | 2008-04-24 | Release date: | 2009-05-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Comparative structural studies on Lys49-phospholipases A(2) from Bothrops genus reveal their myotoxic site. J.Struct.Biol., 167, 2009
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4KF3
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![BU of 4kf3 by Molmil](/molmil-images/mine/4kf3) | Crystal Structure of Myotoxin II (MjTX-II), a myotoxic Lys49-phospholipase A2 from Bothrops moojeni. | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog 2, ISOPROPYL ALCOHOL | Authors: | Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M. | Deposit date: | 2013-04-26 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A2-like. Toxicon, 72C, 2013
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4K06
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![BU of 4k06 by Molmil](/molmil-images/mine/4k06) | Crystal structure of MTX-II from Bothrops brazili venom complexed with polyethylene glycol | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MTX-II, ... | Authors: | Fernandes, C.A.H, Comparetti, E.J, Borges, R.J, Fontes, M.R.M. | Deposit date: | 2013-04-03 | Release date: | 2013-11-13 | Last modified: | 2013-11-27 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural bases for a complete myotoxic mechanism: Crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom. Biochim.Biophys.Acta, 1834, 2013
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4K09
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![BU of 4k09 by Molmil](/molmil-images/mine/4k09) | |
1UMV
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![BU of 1umv by Molmil](/molmil-images/mine/1umv) | Crystal structure of an acidic, non-myotoxic phospholipase A2 from the venom of Bothrops jararacussu | Descriptor: | CALCIUM ION, HYPOTENSIVE PHOSPHOLIPASE A2 | Authors: | Murakami, M.T, Watanabe, L, Cintra, A.C.O, Arni, R.K. | Deposit date: | 2003-08-28 | Release date: | 2003-09-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal Structure of an Acidic Platelet Aggregation Inhibitor and Hypotensive Phospholipase A(2) in the Monomeric and Dimeric States: Insights Into its Oligomeric State Biochem.Biophys.Res.Commun., 323, 2004
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3JR8
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![BU of 3jr8 by Molmil](/molmil-images/mine/3jr8) | Crystal Structure of BthTX-II (Asp49-PLA2 from Bothrops jararacussu snake venom) with calcium ions | Descriptor: | CALCIUM ION, Phospholipase A2 bothropstoxin-2 | Authors: | Borges, R.J, dos Santos, J.I, Fontes, M.R.M. | Deposit date: | 2009-09-08 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class. Proteins, 79, 2011
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