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Crystal structure of human platelet glycoprotein VI in complex with an inhibitory nanobody.
Descriptor:	CALCIUM ION, Nanobody 2, Platelet glycoprotein VI
Authors:	Slater, A, Jonas, E, Watson, S.P.
Deposit date:	2021-02-23
Release date:	2021-03-10
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer. Blood, 137, 2021

Crystal structure of the Factor XII heavy chain reveals an interlocking dimer with a FnII to kringle domain interaction
Descriptor:	Coagulation factor XII-Mie
Authors:	Li, C, Saleem, M, Kaira, B.G, Brown, A, Wilson, C, Philippou, H, Emsley, J.
Deposit date:	2023-04-18
Release date:	2024-03-27
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (3.4 Å)
Cite:	Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery. Blood, 136, 2020

Crystal structure of the GPVI-glenzocimab complex
Descriptor:	CHLORIDE ION, Fab heavy chain, Fab light chain, ...
Authors:	Jandrot-Perrus, M, Lebozec, K, Rose, N, Welin, M, Billiald, P.
Deposit date:	2022-02-10
Release date:	2022-11-16
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.902 Å)
Cite:	Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition. Blood Adv, 7, 2023

Asymmetric complex of Factor XII and kininogen with gC1qR/C1QBP/P32 is governed by allostery
Descriptor:	Coagulation factor XII, Complement component 1 Q subcomponent-binding protein, mitochondrial, ...
Authors:	Kaira, B.G, Emsley, J.
Deposit date:	2019-10-02
Release date:	2020-07-22
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (3.14 Å)
Cite:	Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery. Blood, 136, 2020