6SZW

Asymmetric complex of Factor XII and kininogen with gC1qR/C1QBP/P32 is governed by allostery

Summary for 6SZW

Entry DOI	10.2210/pdb6szw/pdb
Descriptor	Complement component 1 Q subcomponent-binding protein, mitochondrial, Coagulation factor XII, ZINC ION, ... (4 entities in total)
Functional Keywords	contact activation, blood clotting
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	80136.06
Authors	Kaira, B.G.,Emsley, J. (deposition date: 2019-10-02, release date: 2020-07-22, Last modification date: 2024-01-24)
Primary citation	Kaira, B.G.,Slater, A.,McCrae, K.R.,Dreveny, I.,Sumya, U.,Mutch, N.J.,Searle, M.,Emsley, J. Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery. Blood, 136:1685-1697, 2020 Cited by PubMed: 32559765 DOI: 10.1182/blood.2020004818 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.14 Å)

Structure validation