6SZW

Asymmetric complex of Factor XII and kininogen with gC1qR/C1QBP/P32 is governed by allostery

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005759	cellular_component	mitochondrial matrix
B	0005759	cellular_component	mitochondrial matrix
C	0005759	cellular_component	mitochondrial matrix

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue ZN A 301

Chain	Residue
A	ASP185
A	HIS187

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 301

Chain	Residue
B	ASP185
B	HIS187
B	HOH401
B	HOH402

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site_id	AC3
Number of Residues	4
Details	binding site for residue ZN C 301

Chain	Residue
C	HOH404
C	ASP185
C	HIS187
C	HOH402

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Functional Information from PROSITE/UniProt

site_id	PS00023
Number of Residues	42
Details	FN2_1 Fibronectin type-II collagen-binding domain signature. ChfPFqYhrqlyhkCthkgrpgpqpWCattpNFdqdqrWgYC

Chain	Residue	Details
D	CYS28-CYS69

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER87
B	SER87
C	SER87

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site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS91
B	LYS91
C	LYS91

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site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:17693683, ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	TYR188
B	TYR188
C	TYR188

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site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER201
B	SER201
C	SER201

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site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER205
B	SER205
C	SER205

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site_id	SWS_FT_FI6
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	THR214
B	THR214
C	THR214

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