6SZW
Asymmetric complex of Factor XII and kininogen with gC1qR/C1QBP/P32 is governed by allostery
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Complement component 1 Q subcomponent-binding protein, mitochondrial | polymer | 209 | 23826.1 | 3 | UniProt (Q07021) Pfam (PF02330) | Homo sapiens (Human) | ASF/SF2-associated protein p32,Glycoprotein gC1qBP,C1qBP,Hyaluronan-binding protein 1,Mitochondrial matrix protein p32,gC1q-R protein,p33,SF2AP32 |
| 2 | D (D) | Coagulation factor XII | polymer | 71 | 8461.5 | 1 | UniProt (P00748) Pfam (PF00040) | Homo sapiens (Human) | Hageman factor,HAF |
| 3 | E, F, G (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | H, I, J (A, B, C) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A, B, C: 75 - 282 (UniProt: Q07021)
| PDB | External Database | Details |
|---|---|---|
| Met 74 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 79939.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 80136.1 |
