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3OB2
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Crystal structure of c-Cbl TKB domain in complex with double phosphorylated EGFR peptide
分子名称: 12-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL
著者Sun, Q, Sivaraman, J.
登録日2010-08-06
公開日2010-08-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain
Plos One, 5, 2010
3OF8
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BU of 3of8 by Molmil
Structural Basis for Reversible and Irreversible Inhibition of Human Cathepsin L by their Respective Dipeptidyl Glyoxal and Diazomethylketone Inhibitors
分子名称: Cathepsin L1, Nalpha-[(benzyloxy)carbonyl]-N-[(2S)-1-(4-tert-butoxyphenyl)-4-hydroxy-3-oxobutan-2-yl]-L-phenylalaninamide
著者Shenoy, R.T, Sivaraman, J.
登録日2010-08-14
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for reversible and irreversible inhibition of human cathepsin L by their respective dipeptidyl glyoxal and diazomethylketone inhibitors.
J.Struct.Biol., 173, 2011
3OF9
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Structural Basis for Irreversible Inhibition of Human Cathepsin L by a Diazomethylketone Inhibitor
分子名称: Cathepsin L1, Nalpha-[(benzyloxy)carbonyl]-N-[(1S)-1-(4-tert-butoxybenzyl)-3-diazo-2-oxopropyl]-L-phenylalaninamide
著者Shenoy, R.T, Sivaraman, J.
登録日2010-08-14
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.761 Å)
主引用文献Structural basis for reversible and irreversible inhibition of human cathepsin L by their respective dipeptidyl glyoxal and diazomethylketone inhibitors.
J.Struct.Biol., 173, 2011
3PH0
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BU of 3ph0 by Molmil
Crystal structure of the heteromolecular chaperone, AscE-AscG, from the type III secretion system in Aeromonas hydrophila
分子名称: AscE, AscG
著者Chatterjee, C, Kumar, S, Chakraborty, S, Tan, Y.W, Leung, K.Y, Sivaraman, J, Mok, Y.K.
登録日2010-11-03
公開日2011-07-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the heteromolecular chaperone, AscE-AscG, from the type III secretion system in Aeromonas hydrophila
Plos One, 6, 2011
3PIS
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BU of 3pis by Molmil
Crystal Structure of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1
分子名称: Kazal-type serine protease inhibitor SPI-1
著者Giri, P.K, Tang, X.H, Sivaraman, J.
登録日2010-11-08
公開日2010-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Modifying the Substrate Specificity of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 to Target Thrombin
To be Published
3PLC
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BU of 3plc by Molmil
Crystal structure of Beta-Cardiotoxin, a novel three-finger cardiotoxin from the venom of Ophiophagus hannah
分子名称: Beta-cardiotoxin OH-27
著者Roy, A, Qingxiang, S, Kini, R.M, Sivaraman, J.
登録日2010-11-15
公開日2011-11-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Identification of a alpha-helical molten globule intermediate and structural characterization of beta-cardiotoxin, an all beta-sheet protein isolated from the venom of Ophiophagus hannah (king cobra).
Protein Sci., 28, 2019
3PLF
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BU of 3plf by Molmil
Reverse Binding Mode of MetRD peptide complexed with c-Cbl TKB domain
分子名称: CALCIUM ION, CHLORIDE ION, E3 ubiquitin-protein ligase CBL, ...
著者Sun, Q, Sivaraman, J.
登録日2010-11-15
公開日2010-12-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding
Febs Lett., 585, 2011
3QTL
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BU of 3qtl by Molmil
Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin
分子名称: Kazal-type serine protease inhibitor SPI-1, Subtilisin-like serin protease
著者Shenoy, R.T, Sivaraman, J.
登録日2011-02-23
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for dual-inhibition mechanism of a non-classical kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin.
Plos One, 6, 2011
3T0I
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BU of 3t0i by Molmil
Crystal structure of complex of BT_2972 and AdoHcy, a methyltransferase from Bacteroides thetaiotaomicron
分子名称: Putative methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Kumar, V, Sivaraman, J.
登録日2011-07-20
公開日2011-09-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of complex of BT_2972 and AdoHcy,a methyltransferase from Bacteroides thetaiotaomicron
To be published
3T7R
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BU of 3t7r by Molmil
Crystal structure of apo BVU_3255, a methyltransferase from Bacteroides vulgatus ATCC 8482
分子名称: 3-[(2Z)-3-methylpent-2-en-1-yl]benzene-1,2-diol, Putative methyltransferase
著者Kumar, V, Sivaraman, J.
登録日2011-07-31
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural characterization of BVU_3255, a methyltransferase from human intestine antibiotic resistant pathogen Bacteroides vulgatus
J.Struct.Biol., 2011
3SVZ
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BU of 3svz by Molmil
Crystal structure of apo BT_2972, a methyltransferase from Bacteroides thetaiotaomicron
分子名称: Putative methyltransferase
著者Kumar, V, Sivaraman, J.
登録日2011-07-13
公開日2011-09-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of apo BT_2972, a methyltransferase from Bacteroides thetaiotaomicron
To be published
3T7S
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Crystal structure of complex of SAM and BVU_3255, a methyltransferase from Bacteroides vulgatus ATCC 8482
分子名称: Putative methyltransferase, S-ADENOSYLMETHIONINE
著者Kumar, V, Sivaraman, J.
登録日2011-07-31
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural characterization of BVU_3255, a methyltransferase from human intestine antibiotic resistant pathogen Bacteroides vulgatus
J.Struct.Biol., 2011
3SXJ
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BU of 3sxj by Molmil
Crystal structure of complex of BT_2972 and AdoMet, a methyltransferase from Bacteroides thetaiotaomicron
分子名称: Putative methyltransferase, S-ADENOSYLMETHIONINE
著者Kumar, V, Sivaraman, J.
登録日2011-07-14
公開日2011-09-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of complex of BT_2972 and AdoMet, a methyltransferase from Bacteroides thetaiotaomicron
To be Published
3T7T
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BU of 3t7t by Molmil
Crystal structure of complex of SAH and BVU_3255, a methyltransferase from Bacteroides vulgatus ATCC 8482
分子名称: Putative methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Kumar, V, Sivaraman, J.
登録日2011-07-31
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural characterization of BVU_3255, a methyltransferase from human intestine antibiotic resistant pathogen Bacteroides vulgatus
J.Struct.Biol., 2011
1VIO
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BU of 1vio by Molmil
Crystal structure of pseudouridylate synthase
分子名称: 1,4-BUTANEDIOL, Ribosomal small subunit pseudouridine synthase A
著者Structural GenomiX
登録日2003-12-01
公開日2003-12-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.
Acta Crystallogr.,Sect.F, 61, 2005
1CS8
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BU of 1cs8 by Molmil
CRYSTAL STRUCTURE OF PROCATHEPSIN L
分子名称: HUMAN PROCATHEPSIN L
著者Cygler, M, Coulombe, R.
登録日1999-08-17
公開日1999-08-23
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
2NMP
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BU of 2nmp by Molmil
Crystal structure of human Cystathionine gamma lyase
分子名称: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE
著者Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van-den-Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2006-10-23
公開日2006-11-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S
J.Biol.Chem., 284, 2009
7WHU
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BU of 7whu by Molmil
Human Neutrophil Elastase in-complex with Ecotin Peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ecotin Peptide, ...
著者Shankar, S, Jayaraman, S.
登録日2021-12-31
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Sequence preference and scaffolding requirement for the inhibition of human neutrophil elastase by ecotin peptide
Protein Sci., 31, 2022
1FC5
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BU of 1fc5 by Molmil
CRYSTAL STRUCTURE OF MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN
分子名称: MAGNESIUM ION, MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN
著者Huang, W, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2000-07-17
公開日2001-07-25
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of Escherichia coli MoeA, a protein from the molybdopterin synthesis pathway.
J.Mol.Biol., 310, 2001
3CZD
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BU of 3czd by Molmil
Crystal structure of human glutaminase in complex with L-glutamate
分子名称: GLUTAMIC ACID, GLYCEROL, Glutaminase kidney isoform, ...
著者Karlberg, T, Welin, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wikstrom, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日2008-04-29
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3COG
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BU of 3cog by Molmil
Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine
分子名称: (2S)-2-aminopent-4-enoic acid, Cystathionine gamma-lyase, DI(HYDROXYETHYL)ETHER, ...
著者Collins, R, Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Schuler, H, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Sagermark, J, Busam, R.D, Welin, M, Weigelt, J, Wikstrom, M, Structural Genomics Consortium (SGC)
登録日2008-03-28
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S.
J.Biol.Chem., 284, 2009
3C0K
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Crystal Structure of a ribosomal RNA methyltranferase
分子名称: UPF0064 protein yccW
著者Subramanian, S, Jayaraman, S, Bujnicki, J.
登録日2008-01-21
公開日2008-11-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes
J.Mol.Biol., 383, 2008
7E50
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Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI
分子名称: AAEL006007-PA, GLYCEROL, Plasminogen, ...
著者Varsha, A.W, Jobichen, C, Mok, Y.K.
登録日2021-02-16
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor.
Protein Sci., 31, 2022
1R8K
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PDXA PROTEIN; NAD-DEPENDENT DEHYDROGENASE/CARBOXYLASE; SUBUNIT OF PYRIDOXINE PHOSPHATE BIOSYNTHETIC PROTEIN PDXJ-PDXA [SALMONELLA TYPHIMURIUM]
分子名称: 4-hydroxythreonine-4-phosphate dehydrogenase 1, CHLORIDE ION, COBALT (II) ION, ...
著者Osipiuk, J, Quartey, P, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2003-10-27
公開日2003-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of NAD-dependent dehydrogenase/carboxylase of Salmonella typhimurium
to be published
3UV1
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Crystal structure a major allergen from dust mite
分子名称: Der f 7 allergen
著者Tan, K.W, Kumar, T, Chew, F.T, Mok, Y.K.
登録日2011-11-29
公開日2012-10-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Der f 7, a Dust Mite Allergen from Dermatophagoides farinae.
Plos One, 7, 2012

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