7WHU
Human Neutrophil Elastase in-complex with Ecotin Peptide
Summary for 7WHU
| Entry DOI | 10.2210/pdb7whu/pdb |
| Descriptor | Neutrophil elastase, Ecotin Peptide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
| Functional Keywords | inhibition, elastase, serine protease, immune system |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 122833.94 |
| Authors | Shankar, S.,Jayaraman, S. (deposition date: 2021-12-31, release date: 2022-07-06, Last modification date: 2023-11-29) |
| Primary citation | Bagga, T.,Loh, S.N.,Sivaraman, J.,Shankar, S. Sequence preference and scaffolding requirement for the inhibition of human neutrophil elastase by ecotin peptide Protein Sci., 31:933-941, 2022 Cited by DOI: 10.1002/pro.4274PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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