7WHU

Human Neutrophil Elastase in-complex with Ecotin Peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (D, A, B, C)	Neutrophil elastase	polymer	267	28549.1	4	UniProt (P08246) Pfam (PF00089)	Homo sapiens (human)	Bone marrow serine protease,Elastase-2,Human leukocyte elastase,HLE,Medullasin,PMN elastase
2	E, F, G, H (E, F, G, H)	Ecotin Peptide	polymer	8	806.9	4		Homo sapiens (human)
3	I, L, O, P (P, K, N, O)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	4	In PDB GlyTouCan (G21290RB)
4	J (I)	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
5	K (J)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
6	M (L)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
7	N (M)	alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G11971MR)
8	Q, S, V, W, X... (D, A, B, C)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
9	AA, R, T, U, Z (C, D, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
10	BA, CA, DA, EA, FA... (D, A, B, C, F...)	water	water		18.0	28	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	117423.9
Branched	Number of molecules	8
	Total formula weight	4377.1
Non-Polymers*	Number of molecules	11
	Total formula weight	1032.9
All*	Total formula weight	122833.9

*Water molecules are not included.