7WHU

Human Neutrophil Elastase in-complex with Ecotin Peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006508	biological_process	proteolysis
B	0004252	molecular_function	serine-type endopeptidase activity
B	0006508	biological_process	proteolysis
C	0004252	molecular_function	serine-type endopeptidase activity
C	0006508	biological_process	proteolysis
D	0004252	molecular_function	serine-type endopeptidase activity
D	0006508	biological_process	proteolysis

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. MSAAHC

Chain	Residue	Details
D	MET52-CYS57

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site_id	PS00135
Number of Residues	12
Details	TRYPSIN_SER Serine proteases, trypsin family, serine active site. GVcfGDSGSPLV

Chain	Residue	Details
D	GLY175-VAL186

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: Charge relay system => ECO:0000269|PubMed:2911584

Chain	Residue	Details
D	HIS56
C	HIS56
C	ASP98
C	SER181
D	ASP98
D	SER181
A	HIS56
A	ASP98
A	SER181
B	HIS56
B	ASP98
B	SER181

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218

Chain	Residue	Details
D	ASN71
A	ASN71
B	ASN71
C	ASN71

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site_id	SWS_FT_FI3
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26274980, ECO:0000269|PubMed:3550808

Chain	Residue	Details
D	ASN105
A	ASN105
B	ASN105
C	ASN105

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site_id	SWS_FT_FI4
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:3550808

Chain	Residue	Details
D	ASN154
A	ASN154
B	ASN154
C	ASN154

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