2NMP
Crystal structure of human Cystathionine gamma lyase
Summary for 2NMP
Entry DOI | 10.2210/pdb2nmp/pdb |
Descriptor | Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total) |
Functional Keywords | amino-acid biosynthesis, lyase, pyridoxal phopshate, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P32929 |
Total number of polymer chains | 4 |
Total formula weight | 178084.11 |
Authors | Karlberg, T.,Uppenberg, J.,Arrowsmith, C.,Berglund, H.,Busam, R.D.,Collins, R.,Edwards, A.,Ericsson, U.B.,Flodin, S.,Flores, A.,Graslund, S.,Hallberg, B.M.,Hammarstrom, M.,Hogbom, M.,Johansson, I.,Kotenyova, T.,Magnusdottir, A.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,van-den-Berg, S.,Wallden, K.,Weigelt, J.,Holmberg-Schiavone, L.,Structural Genomics Consortium (SGC) (deposition date: 2006-10-23, release date: 2006-11-07, Last modification date: 2023-10-25) |
Primary citation | Sun, Q.,Collins, R.,Huang, S.,Holmberg-Schiavone, L.,Anand, G.S.,Tan, C.-H.,van-den-Berg, S.,Deng, L.-W.,Moore, P.K.,Karlberg, T.,Sivaraman, J. Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S J.Biol.Chem., 284:3076-3085, 2009 Cited by PubMed: 19019829DOI: 10.1074/jbc.M805459200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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