7M3Q
| Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ... | 著者 | Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-03-18 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) To be published
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7T1K
| Crystal structure of a superbinder Fes SH2 domain (sFes1) in complex with a high affinity phosphopeptide | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MALONATE ION, ... | 著者 | Martyn, G.D, Singer, A.U, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-12-02 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
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7T1L
| Crystal structure of a superbinder Fes SH2 domain (sFesS) in complex with a high affinity phosphopeptide | 分子名称: | CHLORIDE ION, SODIUM ION, Synthetic phosphotyrosine-containing Ezrin-derived peptide, ... | 著者 | Martyn, G.D, Singer, A.U, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-12-02 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
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7T1U
| Crystal structure of a superbinder Src SH2 domain (sSrcF) in complex with a high affinity phosphopeptide | 分子名称: | Proto-oncogene tyrosine-protein kinase Src, Synthetic phosphopeptide, ZINC ION | 著者 | Martyn, G.D, Singer, A.U, Manczyk, N, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-12-02 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
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4DCA
| Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, ADP-bound | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside phosphotransferase, MAGNESIUM ION | 著者 | Stogios, P.J, Minasov, G, Singer, A.U, Tan, K, Nocek, B, Evdokimova, E, Egorova, O, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-01-17 | 公開日 | 2012-02-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, ADP-bound TO BE PUBLISHED
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1XO5
| Crystal structure of CIB1, an EF-hand, integrin and kinase-binding protein | 分子名称: | CALCIUM ION, Calcium and integrin-binding protein 1 | 著者 | Gentry, H.R, Singer, A.U, Betts, L, Yang, C, Ferrara, J.D, Parise, L.V, Sondek, J. | 登録日 | 2004-10-05 | 公開日 | 2004-12-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural and Biochemical Characterization of CIB1 Delineates a New Family of EF-hand-containing Proteins J.Biol.Chem., 280, 2005
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3UZR
| Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, apo form | 分子名称: | 1,2-ETHANEDIOL, Aminoglycoside phosphotransferase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Stogios, P.J, Minasov, G, Singer, A.U, Tan, K, Nocek, B, Evdokimova, E, Egorova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-12-07 | 公開日 | 2011-12-21 | 最終更新日 | 2011-12-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, apo form TO BE PUBLISHED
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2PLE
| NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE | 分子名称: | PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF | 著者 | Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. | 登録日 | 1994-08-19 | 公開日 | 1995-01-26 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
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2PLD
| NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE | 分子名称: | PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF | 著者 | Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. | 登録日 | 1994-08-19 | 公開日 | 1995-01-26 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
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3NUQ
| Structure of a putative nucleotide phosphatase from Saccharomyces cerevisiae | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Dong, A, Yang, C, Singer, A.U, Evdokimova, E, Kudritsdka, M, Brown, G, Edwards, A.M, Joachimiak, A, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-07-07 | 公開日 | 2010-08-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of a putative nucleotide phosphatase from Saccharomyces cerevisiae To be Published
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3P48
| Structure of the yeast dUTPase DUT1 in complex with dUMPNPP | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION | 著者 | Petit, P, Singer, A.U, Evdokimova, E, Kudritska, M, Edwards, A.M, Yakunin, A.F, Savchenko, A, Ontario Centre for Structural Proteomics (OCSP) | 登録日 | 2010-10-06 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme. Biochem.J., 437, 2011
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7LUL
| Structure of the MM2 Erbin PDZ variant in complex with a high-affinity peptide | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-02-22 | 公開日 | 2021-07-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
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6UBH
| Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide | 分子名称: | Erbin, SODIUM ION, peptide | 著者 | Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2019-09-11 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
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6Q0M
| Structure of Erbin PDZ derivative E-14 with a high-affinity peptide | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6Q0N
| Structure of the Erbin PDB domain in complex with a high-affinity peptide | 分子名称: | Erbin, peptide | 著者 | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6Q0U
| Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide | 分子名称: | 1,2-ETHANEDIOL, Erbin, peptide | 著者 | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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2Q16
| Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with ITP | 分子名称: | CALCIUM ION, HAM1 protein homolog, INOSINE 5'-TRIPHOSPHATE, ... | 著者 | Singer, A.U, Lam, R, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F. | 登録日 | 2007-05-23 | 公開日 | 2008-02-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374, 2007
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2QH1
| Structure of TA289, a CBS-rubredoxin-like protein, in its Fe+2-bound state | 分子名称: | FE (II) ION, Hypothetical protein Ta0289 | 著者 | Singer, A.U, Proudfoot, M, Brown, G, Xu, L, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2007-06-29 | 公開日 | 2008-02-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain. J.Mol.Biol., 375, 2008
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8CX9
| Structure of the SARS-COV2 PLpro (C111S) in complex with a dimeric Ubv that inhibits activity by an unusual allosteric mechanism | 分子名称: | BROMIDE ION, CHLORIDE ION, Papain-like protease nsp3, ... | 著者 | Singer, A.U, Slater, C.L, Patel, A, Russel, R, Mark, B.L, Sidhu, S.S. | 登録日 | 2022-05-20 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. Plos Pathog., 18, 2022
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3QVM
| The structure of olei00960, a hydrolase from Oleispira antarctica | 分子名称: | CALCIUM ION, CHLORIDE ION, Olei00960, ... | 著者 | Singer, A.U, Kagan, O, Kim, Y, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-02-25 | 公開日 | 2011-04-13 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun, 4, 2013
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3BRM
| Crystal structure of the covalent complex between the Bacillus subtilis glutaminase YbgJ and 5-oxo-L-norleucine formed by reaction of the protein with 6-diazo-5-oxo-L-norleucine | 分子名称: | 5-OXO-L-NORLEUCINE, Glutaminase 1 | 著者 | Singer, A.U, Kim, Y, Dementieva, I, Vinokour, E, Joachimiak, A, Savchenko, A, Yakunin, A. | 登録日 | 2007-12-21 | 公開日 | 2008-05-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis. Biochemistry, 47, 2008
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2PYU
| Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with IMP | 分子名称: | 1,2-ETHANEDIOL, INOSINIC ACID, Inosine Triphosphate Pyrophosphatase RdgB | 著者 | Singer, A.U, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F. | 登録日 | 2007-05-16 | 公開日 | 2008-03-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374, 2007
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3M16
| Structure of a Transaldolase from Oleispira antarctica | 分子名称: | Transaldolase | 著者 | Singer, A.U, Kagan, O, Zhang, R, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-03-04 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. Nat Commun, 4, 2013
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3OI7
| Structure of the structure of the H13A mutant of Ykr043C in complex with sedoheptulose-1,7-bisphosphate | 分子名称: | 1,2-ETHANEDIOL, 1,7-di-O-phosphono-beta-D-altro-hept-2-ulofuranose, GLYCEROL, ... | 著者 | Singer, A.U, Xu, X, Dong, A, Cui, H, Clasquin, M.F, Caudy, A.A, Edwards, A.M, Savchenko, A, Joachimiak, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2010-08-18 | 公開日 | 2010-11-17 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Riboneogenesis in yeast. Cell(Cambridge,Mass.), 145, 2011
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3DRW
| Crystal Structure of a Phosphofructokinase from Pyrococcus horikoshii OT3 with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, ADP-specific phosphofructokinase, SODIUM ION | 著者 | Singer, A.U, Skarina, T, Kochinyan, S, Brown, G, Cuff, M.E, Edwards, A.M, Joachimiak, A, Savchenko, A, Yakunin, A.F, Jia, Z, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-07-11 | 公開日 | 2008-12-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | ADP-dependent 6-phosphofructokinase from Pyrococcus horikoshii OT3: structure determination and biochemical characterization of PH1645. J.Biol.Chem., 284, 2009
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