4QEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qex by Molmil](/molmil-images/mine/4qex) | Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217 | Descriptor: | Antibody Heavy Chain, Antibody Light Chain, Erythrocyte-binding antigen-175 | Authors: | Chen, E, Paing, M.M, Salinas, N, Sim, B.K, Tolia, N.H. | Deposit date: | 2014-05-19 | Release date: | 2014-06-04 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175. Plos Pathog., 9, 2013
|
|
1ZRO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zro by Molmil](/molmil-images/mine/1zro) | Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose | Descriptor: | CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II | Authors: | Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L. | Deposit date: | 2005-05-19 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum. Cell(Cambridge,Mass.), 122, 2005
|
|
1ZRL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zrl by Molmil](/molmil-images/mine/1zrl) | Crystal structure of EBA-175 Region II (RII) | Descriptor: | CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II | Authors: | Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L. | Deposit date: | 2005-05-19 | Release date: | 2005-08-09 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum. Cell(Cambridge,Mass.), 122, 2005
|
|
6B5M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b5m by Molmil](/molmil-images/mine/6b5m) | |
6B5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b5t by Molmil](/molmil-images/mine/6b5t) | Structure of PfCSP peptide 29 with human antibody CIS42 | Descriptor: | AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ... | Authors: | Pancera, M, Weidle, C. | Deposit date: | 2017-09-29 | Release date: | 2018-03-21 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (2.222 Å) | Cite: | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
|
|
6B5N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b5n by Molmil](/molmil-images/mine/6b5n) | Structure of PfCSP peptide 25 with human protective antibody CIS43 | Descriptor: | CIS43 Fab Heavy chain, CIS43 Fab Light chain, pfCSP peptide 25: ASN-VAL-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP | Authors: | Pancera, M, Weidle, C. | Deposit date: | 2017-09-29 | Release date: | 2018-03-21 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
|
|
6B5O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b5o by Molmil](/molmil-images/mine/6b5o) | Structure of PfCSP peptide 29 with human protective antibody CIS43 | Descriptor: | CIS43 Fab Heavy chain, CIS43 Fab Light chain, PfCSP peptide 29: ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN | Authors: | Pancera, M, Weidle, C. | Deposit date: | 2017-09-29 | Release date: | 2018-03-21 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
|
|
6B5L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b5l by Molmil](/molmil-images/mine/6b5l) | Structure of PfCSP peptide 20 with human protective antibody CIS43 | Descriptor: | CIS43 Fab Heavy chain, CIS43 Fab Light Chain, PfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL | Authors: | Pancera, M, Weidle, C. | Deposit date: | 2017-09-29 | Release date: | 2018-03-21 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
|
|
6B5S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b5s by Molmil](/molmil-images/mine/6b5s) | Structure of PfCSP peptide 25 with human antibody CIS42 | Descriptor: | AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ... | Authors: | Pancera, M, Weidle, C. | Deposit date: | 2017-09-29 | Release date: | 2018-03-21 | Last modified: | 2019-01-09 | Method: | X-RAY DIFFRACTION (1.983 Å) | Cite: | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
|
|
6B5R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b5r by Molmil](/molmil-images/mine/6b5r) | Structure of PfCSP peptide 21 with human antibody CIS42 | Descriptor: | CIS42 Fab Heavy chain, CIS42 Fab Light chain, PfCSP peptide 21: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN | Authors: | Pancera, M, Weidle, C. | Deposit date: | 2017-09-29 | Release date: | 2018-03-21 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (1.775 Å) | Cite: | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
|
|
6B5P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b5p by Molmil](/molmil-images/mine/6b5p) | Structure of PfCSP peptide 20 with human antibody CIS42 | Descriptor: | CIS42 Fab Heavy chain, CIS42 Fab Light chain, pfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP | Authors: | Pancera, M, Weidle, C. | Deposit date: | 2017-09-29 | Release date: | 2018-03-21 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (2.297 Å) | Cite: | A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
|
|
6BQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bqb by Molmil](/molmil-images/mine/6bqb) | MGG4 Fab in complex with peptide | Descriptor: | GLYCEROL, MGG4 Fab heavy chain, MGG4 Fab light chain, ... | Authors: | Oyen, D, Tan, J, Lanzavecchia, A, Wilson, I.A. | Deposit date: | 2017-11-27 | Release date: | 2018-03-07 | Last modified: | 2018-04-25 | Method: | X-RAY DIFFRACTION (1.769 Å) | Cite: | A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nat. Med., 24, 2018
|
|
4K2U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k2u by Molmil](/molmil-images/mine/4k2u) | Crystal structure of PfEBA-175 F1 in complex with R218 antibody Fab fragment | Descriptor: | Antibody Heavy Chain, Antibody Light Chain, Erythrocyte binding antigen 175, ... | Authors: | Tolia, N.H. | Deposit date: | 2013-04-09 | Release date: | 2013-06-12 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175. Plos Pathog., 9, 2013
|
|
6D01
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d01 by Molmil](/molmil-images/mine/6d01) | Crystal structure of 1210 Fab in complex with circumsporozoite protein NANP5 | Descriptor: | 1,2-ETHANEDIOL, 1210 Antibody, Light chain, ... | Authors: | Scally, S.W, Bosch, A, Imkeller, K, Wardemann, H, Julien, J.P. | Deposit date: | 2018-04-09 | Release date: | 2018-06-13 | Last modified: | 2018-07-04 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science, 360, 2018
|
|
6D11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d11 by Molmil](/molmil-images/mine/6d11) | Crystal structure of 1450 Fab in complex with circumsporozoite protein NANP5 | Descriptor: | 1450 Antibody, Heavy chain, Light chain, ... | Authors: | Scally, S.W, Bosch, A, Imkeller, K, Wardemann, H, Julien, J.P. | Deposit date: | 2018-04-11 | Release date: | 2018-06-13 | Last modified: | 2018-07-04 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science, 360, 2018
|
|
6B0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b0s by Molmil](/molmil-images/mine/6b0s) | Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody | Descriptor: | 1710 antibody, heavy chain, light chain, ... | Authors: | Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | Deposit date: | 2017-09-15 | Release date: | 2017-11-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection. J. Exp. Med., 215, 2018
|
|
6B0W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b0w by Molmil](/molmil-images/mine/6b0w) | Crystal structure of the anti-circumsporozoite protein 1710 antibody | Descriptor: | 1710 antibody, heavy chain, light chain, ... | Authors: | Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | Deposit date: | 2017-09-15 | Release date: | 2017-11-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection. J. Exp. Med., 215, 2018
|
|
6D0X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d0x by Molmil](/molmil-images/mine/6d0x) | Crystal structure of chimeric H.2140 / K.1210 Fab in complex with circumsporozoite protein NANP3 | Descriptor: | 1210 Antibody, light chain, 2140 Antibody, ... | Authors: | Scally, S.W, Bosch, A, Imkeller, K, Wardemann, H, Julien, J.P. | Deposit date: | 2018-04-11 | Release date: | 2018-06-13 | Last modified: | 2018-07-04 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science, 360, 2018
|
|