8ILQ
| Structure of SFTSV Gn-Gc heterodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein | Authors: | Du, S, Peng, R, Qi, J, Li, C. | Deposit date: | 2023-03-04 | Release date: | 2023-09-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of severe fever with thrombocytopenia syndrome virus. Nat Commun, 14, 2023
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8ITT
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8ITR
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2G6Q
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7V7M
| crystal structure of SARS-CoV-2 3CL protease | Descriptor: | 3C-like proteinase | Authors: | Yi, Y, Zhang, M, Ye, M. | Deposit date: | 2021-08-21 | Release date: | 2022-06-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Schaftoside inhibits 3CL pro and PL pro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19. Acta Pharm Sin B, 12, 2022
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5U2J
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5UQ9
| Crystal structure of 6-phosphogluconate dehydrogenase with ((4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate | Descriptor: | 6-phosphogluconate dehydrogenase, decarboxylating, [(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl dihydrogen phosphate | Authors: | Leonard, P.G. | Deposit date: | 2017-02-07 | Release date: | 2018-08-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation. Cell Rep, 26, 2019
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6WW4
| Crystal structure of HERC2 ZZ domain in complex with histone H3 tail | Descriptor: | GLYCEROL, Histone H3.1,E3 ubiquitin-protein ligase HERC2, ZINC ION | Authors: | Liu, J, Vann, K.R, Kutateladze, T.G. | Deposit date: | 2020-05-07 | Release date: | 2020-08-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.252 Å) | Cite: | Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1. Structure, 28, 2020
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6WXK
| PHF23 PHD Domain Apo | Descriptor: | PHD finger protein 23, ZINC ION | Authors: | Vann, K.R, Zhang, J, Zhang, Y, Kutateladze, T. | Deposit date: | 2020-05-11 | Release date: | 2020-07-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion. Nat Commun, 11, 2020
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6WW3
| Crystal structure of HERC2 ZZ domain in complex with SUMO1 tail | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SUMO1 linked HERC2 ZZ domain (Small ubiquitin-related modifier 1,E3 ubiquitin-protein ligase HERC2), ... | Authors: | Liu, J, Vann, K.R, Kutateladze, T.G. | Deposit date: | 2020-05-07 | Release date: | 2020-08-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1. Structure, 28, 2020
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3T7U
| A NeW Crystal structure of APC-ARM | Descriptor: | Adenomatous polyposis coli protein, PHOSPHATE ION | Authors: | Zhang, Z, Wu, G. | Deposit date: | 2011-07-31 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility Biochem.Biophys.Res.Commun., 412, 2011
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3VXK
| Crystal structure of OsD14 | Descriptor: | Dwarf 88 esterase | Authors: | Xue, Y.-L, Miyakawa, T, Hou, F, Qin, H.-M, Tanokura, M. | Deposit date: | 2012-09-18 | Release date: | 2013-09-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular mechanism of strigolactone perception by DWARF14 Nat Commun, 4, 2013
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3WIO
| Crystal structure of OSD14 in complex with hydroxy D-ring | Descriptor: | (5R)-5-hydroxy-3-methylfuran-2(5H)-one, Probable strigolactone esterase D14 | Authors: | Xue, Y.-L, Miyakawa, T, Hou, F, Qin, H.-M, Tanokura, M. | Deposit date: | 2013-09-22 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular mechanism of strigolactone perception by DWARF14 Nat Commun, 4, 2013
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5BRR
| Michaelis complex of tPA-S195A:PAI-1 | Descriptor: | GLYCEROL, Plasminogen activator inhibitor 1, TRIETHYLENE GLYCOL, ... | Authors: | Gong, L. | Deposit date: | 2015-06-01 | Release date: | 2015-09-02 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1 J.Biol.Chem., 290, 2015
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7BWJ
| crystal structure of SARS-CoV-2 antibody with RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | Authors: | Wang, X, Ge, J. | Deposit date: | 2020-04-14 | Release date: | 2020-06-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature, 584, 2020
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7XMX
| Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three F61 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F61 heavy chain, F61 light chain, ... | Authors: | Wang, X, Li, X. | Deposit date: | 2022-04-27 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages. Cell Discov, 8, 2022
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7XST
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7XMZ
| Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three D2 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ... | Authors: | Wang, X, Li, X. | Deposit date: | 2022-04-27 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages. Cell Discov, 8, 2022
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5HJB
| AF9 YEATS in complex with histone H3 Crotonylation at K9 | Descriptor: | Protein AF-9, peptide of Histone H3.1 | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-12 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain Mol.Cell, 62, 2016
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5HJD
| AF9 YEATS in complex with histone H3 Crotonylation at K18 | Descriptor: | COPPER (II) ION, Protein AF-9, SULFATE ION, ... | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-13 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. Mol.Cell, 62, 2016
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5HD2
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5HJC
| BRD3 second bromodomain in complex with histone H3 acetylation at K18 | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ... | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-13 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain Mol.Cell, 62, 2016
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5HLN
| X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH CHIR99021 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHIR99021, Glycogen synthase kinase-3 beta, ... | Authors: | White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K. | Deposit date: | 2016-01-15 | Release date: | 2016-05-25 | Last modified: | 2016-07-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. Acs Chem.Biol., 11, 2016
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5HLP
| X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH BRD3937 | Descriptor: | 4-(2-methoxyphenyl)-3,7,7-trimethyl-1,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta | Authors: | White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K. | Deposit date: | 2016-01-15 | Release date: | 2016-05-25 | Last modified: | 2016-07-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. Acs Chem.Biol., 11, 2016
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5IOK
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