2EXG
 
 | | Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain | | 分子名称: | (5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE, Afadin | | 著者 | Joshi, M, Vargas, C, Boisguerin, P, Krause, G, Schade, M, Oschkinat, H. | | 登録日 | 2005-11-08 | | 公開日 | 2006-10-17 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
Angew.Chem.Int.Ed.Engl., 45, 2006
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1IUB
 | | Fucose-specific lectin from Aleuria aurantia (Hg-derivative form) | | 分子名称: | CHLORIDE ION, Fucose-specific lectin, MERCURY (II) ION, ... | | 著者 | Fujihashi, M, Peapus, D.H, Kamiya, N, Nagata, Y, Miki, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-03-01 | | 公開日 | 2003-09-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal Structure of Fucose-Specific Lectin from Aleuria aurantia Binding Ligands at Three of Its Five Sugar Recognition Sites
Biochemistry, 42, 2003
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1C7Y
 | | E.COLI RUVA-HOLLIDAY JUNCTION COMPLEX | | 分子名称: | DNA (5'-D(P*DAP*DAP*DGP*DTP*DTP*DGP*DGP*DGP*DAP*DTP*DTP*DGP*DT)-3'), DNA (5'-D(P*DCP*DAP*DAP*DTP*DCP*DCP*DCP*DAP*DAP*DCP*DTP*DT)-3'), DNA (5'-D(P*DCP*DGP*DAP*DAP*DTP*DGP*DTP*DGP*DTP*DGP*DTP*DCP*DT)-3'), ... | | 著者 | Ariyoshi, M, Nishino, T, Iwasaki, H, Shinagawa, H, Morikawa, K. | | 登録日 | 2000-04-03 | | 公開日 | 2000-07-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of the holliday junction DNA in complex with a single RuvA tetramer.
Proc.Natl.Acad.Sci.USA, 97, 2000
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6LTG
 | | Crystal structure of the Fab fragment of murine monoclonal antibody OHV-3 against Human herpesvirus 6B | | 分子名称: | MAGNESIUM ION, antibody Fab fragment H-chain, antibody Fab fragment L-chain | | 著者 | Nishimura, M, Novita, B.D, Kato, T, Tjan, L.H, Wang, B, Wakata, A, Poetranto, A.L, Kawabata, A, Tang, H, Aoshi, T, Mori, Y. | | 登録日 | 2020-01-22 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural basis for the interaction of human herpesvirus 6B tetrameric glycoprotein complex with the cellular receptor, human CD134.
Plos Pathog., 16, 2020
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6LKT
 | | Crystal structure of the Fab fragment of murine monoclonal antibody KH-1 against Human herpesvirus 6B | | 分子名称: | antibody Fab Fragment L-chain, antibody Fab fragment H chain | | 著者 | Nishimura, M, Novita, B.D, Kato, T, Tjan, L.H, Wang, B, Wakata, A, Poetranto, A.L, Kawabata, A, Tang, H, Aoshi, T, Mori, Y. | | 登録日 | 2019-12-20 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the interaction of human herpesvirus 6B tetrameric glycoprotein complex with the cellular receptor, human CD134.
Plos Pathog., 16, 2020
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2QKS
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1DVE
 | | CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME | | 分子名称: | HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Omata, Y, Kakuta, Y, Sakamoto, H, Noguchi, M, Fukuyama, K. | | 登録日 | 2000-01-20 | | 公開日 | 2000-04-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of rat heme oxygenase-1 in complex with heme.
FEBS Lett., 471, 2000
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7F47
 | | Cryo-EM structure of Rhizobium etli MprF | | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Hypothetical conserved protein, [(2R)-1-[[(2R)-3-[(2S)-2,6-bis(azanyl)hexanoyl]oxy-2-oxidanyl-propoxy]-oxidanyl-phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (E)-octadec-9-enoate | | 著者 | Nishimura, M, Hirano, H, Kobayashi, K, Gill, C.P, Phan, C.N.K, Kise, Y, Kusakizako, T, Yamashita, K, Ito, Y, Roy, H, Nishizawa, T, Nureki, O. | | 登録日 | 2021-06-17 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-06-29 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Cryo-EM structure of Rhizobium etli MprF
To Be Published
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1J02
 | | Crystal Structure of Rat Heme Oxygenase-1-Heme Bound to NO | | 分子名称: | HEME OXYGENASE 1, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Fukuyama, K. | | 登録日 | 2002-10-28 | | 公開日 | 2003-09-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
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1DVG
 | | CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME; SELELENO-METHIONINE DERIVATIVE, MUTATED AT M51T,M93L,M155L,M191L. | | 分子名称: | HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Omata, Y, Kakuta, Y, Sakamoto, H, Noguchi, M, Fukuyama, K. | | 登録日 | 2000-01-20 | | 公開日 | 2000-04-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of rat heme oxygenase-1 in complex with heme.
FEBS Lett., 471, 2000
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1GCQ
 | | CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE | | 著者 | Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. | | 登録日 | 2000-08-08 | | 公開日 | 2001-08-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
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1G4F
 | | NMR STRUCTURE OF THE FIFTH DOMAIN OF HUMAN BETA2-GLYCOPROTEIN I | | 分子名称: | BETA2-GLYCOPROTEIN I | | 著者 | Hoshino, M, Hagihara, Y, Nishii, I, Yamazaki, T, Kato, H, Goto, Y. | | 登録日 | 2000-10-27 | | 公開日 | 2000-11-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Identification of the phospholipid-binding site of human beta(2)-glycoprotein I domain V by heteronuclear magnetic resonance.
J.Mol.Biol., 304, 2000
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1IV8
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1G4G
 | | NMR STRUCTURE OF THE FIFTH DOMAIN OF HUMAN BETA2-GLYCOPROTEIN I | | 分子名称: | BETA2-GLYCOPROTEIN I | | 著者 | Hoshino, M, Hagihara, Y, Nishii, I, Yamazaki, T, Kato, H, Goto, Y. | | 登録日 | 2000-10-27 | | 公開日 | 2000-11-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Identification of the phospholipid-binding site of human beta(2)-glycoprotein I domain V by heteronuclear magnetic resonance.
J.Mol.Biol., 304, 2000
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1GCP
 | | CRYSTAL STRUCTURE OF VAV SH3 DOMAIN | | 分子名称: | VAV PROTO-ONCOGENE | | 著者 | Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. | | 登録日 | 2000-08-08 | | 公開日 | 2001-08-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
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2ZFD
 | | The crystal structure of plant specific calcium binding protein AtCBL2 in complex with the regulatory domain of AtCIPK14 | | 分子名称: | ACETIC ACID, CALCIUM ION, Calcineurin B-like protein 2, ... | | 著者 | Akaboshi, M, Hashimoto, H, Ishida, H, Koizumi, N, Sato, M, Shimizu, T. | | 登録日 | 2007-12-29 | | 公開日 | 2008-02-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | The crystal structure of plant-specific calcium-binding protein AtCBL2 in complex with the regulatory domain of AtCIPK14
J.Mol.Biol., 377, 2008
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4K2O
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4K2P
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1ULX
 | | Partially photolyzed structure of CO-bound heme-heme oxygenase complex | | 分子名称: | CARBON MONOXIDE, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Sakamoto, H, Noguchi, M, Fukuyama, K. | | 登録日 | 2003-09-16 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | CO-trapping site in heme oxygenase revealed by photolysis of its co-bound heme complex: mechanism of escaping from product inhibition
J.Mol.Biol., 341, 2004
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1MQ8
 | | Crystal structure of alphaL I domain in complex with ICAM-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-L, ... | | 著者 | Shimaoka, M, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, McCormack, A, Zhang, R, Joachimiak, A, Takagi, J, Wang, J.-H, Springer, T.A. | | 登録日 | 2002-09-15 | | 公開日 | 2003-01-14 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
Cell(Cambridge,Mass.), 112, 2003
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1N9P
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7WOX
 | | PPARgamma antagonist (MMT-160)- PPARgamma LBD complex | | 分子名称: | N-[[5-(3-phenylprop-2-ynoylamino)-2-propoxy-phenyl]methyl]-4-pyrimidin-2-yl-benzamide, Peroxisome proliferator-activated receptor gamma | | 著者 | Yoshizawa, M, Aoyama, T, Itoh, T, Miyachi, H. | | 登録日 | 2022-01-22 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Arylalkynyl amide-type peroxisome proliferator-activated receptor gamma (PPAR gamma )-selective antagonists covalently bind to the PPAR gamma ligand binding domain with a unique binding mode.
Bioorg.Med.Chem.Lett., 64, 2022
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1MQ9
 | | Crystal structure of high affinity alphaL I domain with ligand mimetic crystal contact | | 分子名称: | Integrin alpha-L, MANGANESE (II) ION | | 著者 | Shimaoka, M, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, McCormack, A, Zhang, R, Joachimiak, A, Takagi, J, Wang, J.-H, Springer, T.A. | | 登録日 | 2002-09-15 | | 公開日 | 2003-01-14 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
Cell(Cambridge,Mass.), 112, 2003
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1MJN
 | | Crystal Structure of the intermediate affinity aL I domain mutant | | 分子名称: | Integrin alpha-L, MAGNESIUM ION | | 著者 | Shimaoka, M, Xiao, T, Liu, J.H, Yang, Y.T, Dong, Y.C, Jun, C.D, McCormack, A, Zhang, R.G, Wang, J.H, Springer, T.A. | | 登録日 | 2002-08-28 | | 公開日 | 2003-01-28 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structures of the alphaL I Domain and its Complex with ICAM-1 reveal a Shape-shifting Pathway for Integrin Regulation
Cell(Cambridge,Mass.), 112, 2003
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6KME
 | | Crystal structure of phytochromobilin synthase from tomato in complex with biliverdin | | 分子名称: | BILIVERDINE IX ALPHA, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Sugishima, M, Wada, K, Fukuyama, K. | | 登録日 | 2019-07-31 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of phytochromobilin synthase in complex with biliverdin IX alpha , a key enzyme in the biosynthesis of phytochrome.
J.Biol.Chem., 295, 2020
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