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5C55
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BU of 5c55 by Molmil
Crystal structure of the Y138F mutant of C.glutamicum N-acetylneuraminic acid lyase in complex with pyruvate
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Dihydrodipicolinate synthase/N-acetylneuraminate lyase, ...
Authors:Shen, Y, Zhou, J, Xie, J.
Deposit date:2015-06-19
Release date:2016-06-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the Y138F mutant of C.glutamicum N-acetylneuraminic acid lyase in complex with pyruvate
To Be Published
3COJ
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BU of 3coj by Molmil
Crystal Structure of the BRCT Domains of Human BRCA1 in Complex with a Phosphorylated Peptide from Human Acetyl-CoA Carboxylase 1
Descriptor: Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein
Authors:Shen, Y, Tong, L.
Deposit date:2008-03-28
Release date:2008-05-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1
Biochemistry, 47, 2008
6BBK
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BU of 6bbk by Molmil
N-terminally truncated group I PilA from Pseudomonas aeruginosa strain 1244
Descriptor: Fimbrial protein
Authors:Shen, Y, Guarne, A, Nguyen, Y, Burrows, L.L.
Deposit date:2017-10-18
Release date:2018-11-21
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:N-terminally truncated group I PilA from Pseudomonas aeruginosa strain 1244
To Be Published
2G54
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BU of 2g54 by Molmil
Crystal structure of Zn-bound human insulin-degrading enzyme in complex with insulin B chain
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, ZINC ION, ...
Authors:Shen, Y, Tang, W.-J.
Deposit date:2006-02-22
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
2G48
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BU of 2g48 by Molmil
crystal structure of human insulin-degrading enzyme in complex with amylin
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, Islet amyloid polypeptide
Authors:Shen, Y, Tang, W.-J.
Deposit date:2006-02-21
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
2G47
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BU of 2g47 by Molmil
Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-40)
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, amyloid protein beta A4
Authors:Shen, Y, Tang, W.-J.
Deposit date:2006-02-21
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
2G49
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BU of 2g49 by Molmil
Crystal structure of human insulin-degrading enzyme in complex with glucagon
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, glucagon preproprotein
Authors:Shen, Y, Tang, W.-J.
Deposit date:2006-02-21
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
2G56
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BU of 2g56 by Molmil
crystal structure of human insulin-degrading enzyme in complex with insulin B chain
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin, Insulin-degrading enzyme
Authors:Shen, Y, Tang, W.-J.
Deposit date:2006-02-22
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Nature, 443, 2006
2GPW
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BU of 2gpw by Molmil
Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Descriptor: Biotin carboxylase
Authors:Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
Deposit date:2006-04-18
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
2GPS
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BU of 2gps by Molmil
Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Descriptor: Biotin carboxylase
Authors:Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
Deposit date:2006-04-18
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
4ZRZ
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BU of 4zrz by Molmil
PlyCB mutant R66E
Descriptor: PlyCB
Authors:Gallagher, D.T, Nelson, D.C, Shen, Y.
Deposit date:2015-05-12
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:A bacteriophage endolysin that eliminates intracellular streptococci.
Elife, 5, 2016
3GJ9
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BU of 3gj9 by Molmil
crystal structure of TIP-1 in complex with c-terminal of Kir2.3
Descriptor: C-terminal peptide from Inward rectifier potassium channel 4, CHLORIDE ION, Tax1-binding protein 3, ...
Authors:Shen, Y.
Deposit date:2009-03-08
Release date:2009-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular mechanism of inward rectifier potassium channel 2.3 regulation by tax-interacting protein-1
J.Mol.Biol., 392, 2009
3I6D
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BU of 3i6d by Molmil
Crystal structure of PPO from bacillus subtilis with AF
Descriptor: 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-NITROBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, ...
Authors:Shen, Y.
Deposit date:2009-07-06
Release date:2009-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insight into unique properties of protoporphyrinogen oxidase from Bacillus subtilis
J.Struct.Biol., 170, 2010
3KKR
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BU of 3kkr by Molmil
Crystal structure of catalytic core domain of BIV integrase in crystal form I
Descriptor: Integrase, NITRATE ION
Authors:Shen, Y.
Deposit date:2009-11-06
Release date:2010-09-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.453 Å)
Cite:Crystal structures of catalytic core domain of BIV integrase: implications for the interaction between integrase and target DNA
Protein Cell, 1, 2010
3KKS
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BU of 3kks by Molmil
Crystal structure of catalytic core domain of BIV integrase in crystal form II
Descriptor: ACETATE ION, GLYCEROL, Integrase
Authors:Shen, Y.
Deposit date:2009-11-06
Release date:2010-09-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of catalytic core domain of BIV integrase: implications for the interaction between integrase and target DNA
Protein Cell, 1, 2010
5H6Z
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BU of 5h6z by Molmil
Crystal structure of Set7, a novel histone methyltransferase in Schizossacharomyces pombe
Descriptor: AMMONIUM ION, DI(HYDROXYETHYL)ETHER, SET domain-containing protein 7, ...
Authors:Mevius, D.E.H.F, Shen, Y, Morishita, M, Carrozzini, B, Caliandro, R, di Luccio, E.
Deposit date:2016-11-15
Release date:2017-11-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Set7 Is a H3K37 Methyltransferase in Schizosaccharomyces pombe and Is Required for Proper Gametogenesis.
Structure, 27, 2019
3NKS
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BU of 3nks by Molmil
Structure of human protoporphyrinogen IX oxidase
Descriptor: 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-NITROBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Shen, Y.
Deposit date:2010-06-21
Release date:2011-04-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insight into human variegate porphyria disease
Faseb J., 25, 2011
3DJ3
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BU of 3dj3 by Molmil
Crystal Structure of C-terminal Truncated TIP-1 (6-113)
Descriptor: Tax1-binding protein 3
Authors:Shen, Y.
Deposit date:2008-06-21
Release date:2008-10-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008
3DIW
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BU of 3diw by Molmil
c-terminal beta-catenin bound TIP-1 structure
Descriptor: Tax1-binding protein 3, decameric peptide form Catenin beta-1
Authors:Shen, Y.
Deposit date:2008-06-21
Release date:2008-10-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008
3DJ1
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BU of 3dj1 by Molmil
crystal structure of TIP-1 wild type
Descriptor: SULFATE ION, Tax1-binding protein 3
Authors:Shen, Y.
Deposit date:2008-06-21
Release date:2008-10-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008
1TE7
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BU of 1te7 by Molmil
Solution NMR Structure of Protein yqfB from Escherichia coli. Northeast Structural Genomics Consortium Target ET99
Descriptor: Hypothetical UPF0267 protein yqfB
Authors:Atreya, H.S, Shen, Y, Yee, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-05-24
Release date:2005-01-04
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:G-Matrix Fourier Transform NOESY-Based Protocol for High-Quality Protein Structure Determination
J.Am.Chem.Soc., 127, 2005
6W6D
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BU of 6w6d by Molmil
Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with SGC6870 inhibitor
Descriptor: (5R)-4-(5-bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one, Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Halabelian, L, Zeng, H, Dong, A, Jin, J, Shen, Y, Kaniskan, H.U, Hutchinson, A, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Brown, P.J, Structural Genomics Consortium (SGC)
Deposit date:2020-03-16
Release date:2020-04-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6.
J.Med.Chem., 64, 2021
5WW0
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BU of 5ww0 by Molmil
Crystal structure of Set7, a novel histone methyltransferase in Schizossacharomyces pombe
Descriptor: SET domain-containing protein 7, SULFATE ION
Authors:Mevius, D.E.H.F, Shen, Y, Morishita, M, Carrozzini, B, Caliandro, R, di Luccio, E.
Deposit date:2016-12-30
Release date:2017-12-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Set7 Is a H3K37 Methyltransferase in Schizosaccharomyces pombe and Is Required for Proper Gametogenesis.
Structure, 27, 2019
4M6T
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BU of 4m6t by Molmil
Structure of human Paf1 and Leo1 complex
Descriptor: RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ...
Authors:Shen, Y, Qin, X.
Deposit date:2013-08-11
Release date:2013-10-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structural insights into Paf1 complex assembly and histone binding
Nucleic Acids Res., 41, 2013
4HWF
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BU of 4hwf by Molmil
Crystal structure of ATBAG3
Descriptor: BAG family molecular chaperone regulator 3, SULFATE ION
Authors:Shen, Y, Fang, S.
Deposit date:2012-11-07
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into plant programmed cell death mediated by BAG proteins in Arabidopsis thaliana.
Acta Crystallogr.,Sect.D, 69, 2013

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