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3G82
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BU of 3g82 by Molmil
Complex of GS-alpha with the catalytic domains of mammalian adenylyl cyclase: complex with MANT-ITP and Mn
Descriptor: 3'-O-{[2-(methylamino)phenyl]carbonyl}inosine 5'-(tetrahydrogen triphosphate), 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 2, ...
Authors:Huebner, M, Mou, T.-C, Sprang, S.R, Seifert, R.
Deposit date:2009-02-11
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:2',3'-(O)-(N-Methyl)anthraniloyl-inosine 5'-triphosphate is the Most Potent Adenylyl Cyclase 1 and 5 Inhibitor Known so far and Effectively Promotes Catalytic Subunit Assembly in the Absence of Forskolin
To be Published
1U0H
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BU of 1u0h by Molmil
STRUCTURAL BASIS FOR THE INHIBITION OF MAMMALIAN ADENYLYL CYCLASE BY MANT-GTP
Descriptor: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase, ...
Authors:Mou, T.C, Gille, A, Seifert, R.J, Sprang, S.R.
Deposit date:2004-07-13
Release date:2004-12-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate.
J.Biol.Chem., 280, 2005
1TL7
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BU of 1tl7 by Molmil
Complex Of Gs- With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With 2'(3')-O-(N-methylanthraniloyl)-guanosine 5'-triphosphate and Mn
Descriptor: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase, ...
Authors:Mou, T.C, Gille, A, Seifert, R.J, Sprang, S.R.
Deposit date:2004-06-09
Release date:2004-12-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate.
J.Biol.Chem., 280, 2005
7OBJ
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BU of 7obj by Molmil
Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803 in complex with cyclic di-AMP (c-di-AMP)
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Membrane-associated protein slr1513
Authors:Selim, K.A, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-22
Release date:2022-02-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diurnal metabolic control in cyanobacteria requires perception of second messenger signaling molecule c-di-AMP by the carbon control protein SbtB.
Sci Adv, 7, 2021
7QDA
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BU of 7qda by Molmil
Crystal structure of CalpL
Descriptor: CalpL, SULFATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Schneberger, N, Hagelueken, G.
Deposit date:2021-11-26
Release date:2022-11-16
Last modified:2023-02-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature, 614, 2023
8B0R
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BU of 8b0r by Molmil
Structure of the CalpL/cA4 complex
Descriptor: Cyclic tetraadenosine monophosphate (cA4), SMODS-associated and fused to various effectors domain-containing protein, SULFATE ION, ...
Authors:Schneberger, N, Hagelueken, G.
Deposit date:2022-09-08
Release date:2022-11-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature, 614, 2023
8B0U
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BU of 8b0u by Molmil
Structure of the CalpL/T10 complex
Descriptor: CalpT10, GLYCEROL, SAVED domain-containing protein, ...
Authors:Schneberger, N, Hagelueken, G.
Deposit date:2022-09-08
Release date:2022-11-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature, 614, 2023
7LT2
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BU of 7lt2 by Molmil
Structure of a dsRNA-sensing cGAS-like receptor from the beetle Tribolium castaneum
Descriptor: MANGANESE (II) ION, Mab-21 domain-containing protein
Authors:Slavik, K.M, Morehouse, B.R, Kranzusch, P.J.
Deposit date:2021-02-18
Release date:2021-07-21
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7LT1
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BU of 7lt1 by Molmil
Structure of the cGAS-like receptor human MB21D2
Descriptor: Protein MB21D2, SULFATE ION
Authors:Morehouse, B.R, Slavik, K.M, Kranzusch, P.J.
Deposit date:2021-02-18
Release date:2021-07-21
Last modified:2021-09-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7MWY
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BU of 7mwy by Molmil
Structure of the drosophila STING cyclic dinucleotide binding domain
Descriptor: STING
Authors:Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
Deposit date:2021-05-17
Release date:2021-07-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7MWZ
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BU of 7mwz by Molmil
Structure of drosophila STING in complex with 3'2'-cGAMP
Descriptor: 3'2'-cGAMP, STING
Authors:Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
Deposit date:2021-05-17
Release date:2021-07-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
2GVD
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BU of 2gvd by Molmil
Complex Of Gs- With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With TNP-ATP and Mn
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 2, Adenylate cyclase type 5, ...
Authors:Mou, T.-C, Sprang, S.R.
Deposit date:2006-05-02
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Broad specificity of Mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors.
Mol.Pharmacol., 70, 2006
2GVZ
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BU of 2gvz by Molmil
Crystal Structure of Complex of Gs- with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with MANT-ATP and Mn
Descriptor: 3'-O-[2-(METHYLAMINO)BENZOYL]ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 2, ...
Authors:Mou, T.-C, Sprang, S.R.
Deposit date:2006-05-03
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Broad specificity of Mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors.
Mol.Pharmacol., 70, 2006

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