1U0H

STRUCTURAL BASIS FOR THE INHIBITION OF MAMMALIAN ADENYLYL CYCLASE BY MANT-GTP

Summary for 1U0H

• Entry DOI: 10.2210/pdb1u0h/pdb
• Related: 1TL7
• Descriptor: Adenylate cyclase, type V, Adenylate cyclase, type II, Guanine nucleotide-binding protein G(s), alpha subunit, ... (9 entities in total)
• Functional Keywords: adenylyl cyclase, gsa, mant-gtp, lyase
• Biological source: Canis lupus familiaris (dog); More
• Cellular location: Membrane; Multi-pass membrane protein: P30803 P26769; Cell membrane; Lipid-anchor (By similarity): P04896
• Total number of polymer chains: 3
• Total formula weight: 96727.52

Authors

Mou, T.C.,Gille, A.,Seifert, R.J.,Sprang, S.R. (deposition date: 2004-07-13, release date: 2004-12-14, Last modification date: 2023-08-23)

• Primary citation: Mou, T.C.,Gille, A.,Fancy, D.A.,Seifert, R.,Sprang, S.R.; Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate.; J.Biol.Chem., 280:7253-7261, 2005; PubMed: 15591060; DOI: 10.1074/jbc.M409076200

Experimental method

X-RAY DIFFRACTION (2.9 Å)