1TL7
Complex Of Gs- With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With 2'(3')-O-(N-methylanthraniloyl)-guanosine 5'-triphosphate and Mn
Summary for 1TL7
Entry DOI | 10.2210/pdb1tl7/pdb |
Related | 1CJK 1CJT 1CJU 1CJV 1CS4 1CUL |
Descriptor | Adenylate cyclase, type V, Adenylate cyclase, type II, Guanine nucleotide-binding protein G(s), alpha subunit, ... (10 entities in total) |
Functional Keywords | adenylyl cyclase, gsa, mant-gtp, lyase |
Biological source | Canis lupus familiaris (dog) More |
Cellular location | Membrane; Multi-pass membrane protein: P30803 P26769 Cell membrane; Lipid-anchor (By similarity): P04896 |
Total number of polymer chains | 3 |
Total formula weight | 96644.54 |
Authors | Mou, T.C.,Gille, A.,Seifert, R.J.,Sprang, S.R. (deposition date: 2004-06-09, release date: 2004-12-14, Last modification date: 2023-08-23) |
Primary citation | Mou, T.C.,Gille, A.,Fancy, D.A.,Seifert, R.,Sprang, S.R. Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate. J.Biol.Chem., 280:7253-7261, 2005 Cited by PubMed: 15591060DOI: 10.1074/jbc.M409076200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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